Detailed information NTG0247770

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CO684_RS12760
• Genome accession: NZ_CP023500
• Coordinates: 2411316..2412203 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain FDAARGOS_412
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2406316..2417203

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CO684_RS12725 (CO684_12725)	-	2406335..2406427 (+)	93	WP_010956583.1	hypothetical protein	-
CO684_RS12730 (CO684_12730)	-	2406535..2407032 (-)	498	WP_001065268.1	glutathione peroxidase	-
CO684_RS12735 (CO684_12735)	-	2407042..2407302 (-)	261	WP_001789910.1	hypothetical protein	-
CO684_RS12745 (CO684_12745)	-	2407684..2407797 (-)	114	WP_011447078.1	hypothetical protein	-
CO684_RS12750 (CO684_12750)	-	2408456..2410456 (-)	2001	WP_000776751.1	ABC transporter permease	-
CO684_RS12755 (CO684_12755)	-	2410453..2411208 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
CO684_RS12760 (CO684_12760)	braS	2411316..2412203 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CO684_RS12765 (CO684_12765)	braR	2412214..2412879 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CO684_RS12770 (CO684_12770)	-	2412905..2413105 (-)	201	WP_000604728.1	hypothetical protein	-
CO684_RS12775 (CO684_12775)	-	2413303..2414727 (+)	1425	WP_000953744.1	alkaline phosphatase	-
CO684_RS14640 (CO684_12780)	-	2414787..2414888 (-)	102	WP_000731972.1	SE2200 family small protein	-
CO684_RS12785 (CO684_12785)	-	2415010..2415465 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
CO684_RS12790 (CO684_12790)	-	2415710..2416471 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=247770 CO684_RS12760 WP_000143419.1 2411316..2412203(-) (braS) [Staphylococcus aureus strain FDAARGOS_412]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=247770 CO684_RS12760 WP_000143419.1 2411316..2412203(-) (braS) [Staphylococcus aureus strain FDAARGOS_412]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997