Detailed information NTG0247764

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CO684_RS08670
• Genome accession: NZ_CP023500
• Coordinates: 1666979..1668022 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain FDAARGOS_412
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1661979..1673022

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CO684_RS08640 (CO684_08640)	-	1662397..1663653 (-)	1257	WP_001795438.1	aminopeptidase	-
CO684_RS08645 (CO684_08645)	-	1663656..1663856 (-)	201	WP_000180461.1	DUF1128 family protein	-
CO684_RS08650 (CO684_08650)	-	1664003..1664467 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
CO684_RS08655 (CO684_08655)	-	1664474..1664749 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
CO684_RS08660 (CO684_08660)	-	1665027..1666244 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
CO684_RS08665 (CO684_08665)	vraR	1666360..1666989 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
CO684_RS08670 (CO684_08670)	vraS	1666979..1668022 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
CO684_RS08675 (CO684_08675)	liaF	1668019..1668720 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
CO684_RS08680 (CO684_08680)	-	1668735..1669121 (-)	387	WP_001110179.1	hypothetical protein	-
CO684_RS08685 (CO684_08685)	map	1669338..1670096 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
CO684_RS08690 (CO684_08690)	-	1670624..1671610 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
CO684_RS08700 (CO684_08700)	-	1672100..1672513 (-)	414	WP_001549145.1	hypothetical protein	-
CO684_RS08705 (CO684_08705)	-	1672542..1672652 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=247764 CO684_RS08670 WP_001017131.1 1666979..1668022(-) (vraS) [Staphylococcus aureus strain FDAARGOS_412]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=247764 CO684_RS08670 WP_001017131.1 1666979..1668022(-) (vraS) [Staphylococcus aureus strain FDAARGOS_412]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1