Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   CO689_RS02125 Genome accession   NZ_CP023497
Coordinates   231957..232673 (+) Length   238 a.a.
NCBI ID   WP_002481723.1    Uniprot ID   -
Organism   Staphylococcus simulans strain FDAARGOS_383     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 226957..237673
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO689_RS02105 (CO689_02105) - 228311..229111 (+) 801 WP_096754310.1 carbon-nitrogen family hydrolase -
  CO689_RS14115 - 229416..229580 (-) 165 WP_158257062.1 delta-lysin family phenol-soluble modulin -
  CO689_RS02110 (CO689_02110) - 229892..230470 (+) 579 WP_002481720.1 accessory gene regulator AgrB -
  CO689_RS02115 (CO689_02115) agrD 230470..230607 (+) 138 WP_002481721.1 cyclic lactone autoinducer peptide AgrD -
  CO689_RS02120 (CO689_02120) agrC 230653..231954 (+) 1302 WP_002481722.1 quorum-sensing sensor histidine kinase AgrC -
  CO689_RS02125 (CO689_02125) agrA 231957..232673 (+) 717 WP_002481723.1 quorum-sensing response regulator AgrA Regulator
  CO689_RS02130 (CO689_02130) - 232748..234232 (-) 1485 WP_002481724.1 GH32 C-terminal domain-containing protein -
  CO689_RS02135 (CO689_02135) - 234468..235556 (+) 1089 WP_002481725.1 YeeE/YedE family protein -
  CO689_RS02140 (CO689_02140) - 235612..235836 (+) 225 WP_096754311.1 sulfurtransferase TusA family protein -
  CO689_RS02145 (CO689_02145) - 235887..236528 (-) 642 WP_002481727.1 redox-sensing transcriptional repressor Rex -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27762.55 Da        Isoelectric Point: 4.6392

>NTDB_id=247706 CO689_RS02125 WP_002481723.1 231957..232673(+) (agrA) [Staphylococcus simulans strain FDAARGOS_383]
MKIIICEDDVQQREHIESIIENYIMIEEKPLEVALSTGDPYEVLEFAKATNEICCYFLDIQLDSDINGIKLGSELRNYDS
VGSIIFITSHSELTYLTFVYKVAAMDFIFKDDPSEMKSRIIDCIETALTRLQLLSKESSLETIELKRGSNSVYVNYDDVM
FFESSAKSHRLIAHLDNRQIEFYGNLKDLSQLDDRFFRCHNSYVINRNNIEEVISKEREVYFKNGEHCYISVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=247706 CO689_RS02125 WP_002481723.1 231957..232673(+) (agrA) [Staphylococcus simulans strain FDAARGOS_383]
GTGAAGATTATTATATGCGAAGATGATGTACAACAGCGTGAACACATTGAATCCATCATTGAAAATTATATTATGATTGA
AGAAAAACCTTTAGAAGTGGCGCTCTCAACGGGTGATCCTTATGAGGTATTAGAATTCGCTAAAGCTACAAATGAGATTT
GTTGTTACTTCTTAGATATTCAGTTAGATTCTGATATTAACGGTATTAAGCTTGGCAGCGAACTTAGAAACTATGATTCT
GTCGGCAGTATTATCTTTATTACTAGCCACAGTGAACTCACTTATCTTACTTTCGTTTATAAAGTAGCAGCCATGGACTT
TATTTTTAAAGATGACCCTTCAGAAATGAAATCTCGAATTATTGATTGTATCGAAACTGCATTGACGAGACTACAGTTGC
TTTCAAAAGAATCTAGTCTCGAAACAATTGAGTTAAAACGTGGCAGTAACTCAGTCTATGTTAATTACGATGATGTCATG
TTCTTTGAATCCTCGGCAAAATCACATCGTTTAATTGCGCATTTAGACAATCGTCAAATCGAATTTTATGGCAACTTAAA
AGATTTAAGCCAATTAGATGACCGCTTCTTCCGTTGTCACAATAGTTACGTCATTAATCGCAATAACATCGAAGAAGTAA
TATCTAAAGAACGTGAGGTCTACTTTAAAAATGGTGAACACTGTTATATCTCAGTAAGAAATTTAAAGAAAATCTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

79.412

100

0.794

Multiple sequence alignment