Detailed information NTG0024745

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: M28_RS09185
• Genome accession: NC_007296
• Coordinates: 1809727..1810494 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes MGAS6180
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1804727..1815494

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M28_RS09170 (M28_Spy1788)	hexB	1805245..1807227 (-)	1983	WP_044564897.1	DNA mismatch repair endonuclease MutL	Machinery gene
M28_RS09175 (M28_Spy1789)	-	1807322..1808473 (-)	1152	WP_003058754.1	tyrosine-type recombinase/integrase	-
M28_RS09180 (M28_Spy1790)	-	1808722..1808865 (+)	144	WP_011185066.1	putative holin-like toxin	-
M28_RS09185 (M28_Spy1791)	irvR	1809727..1810494 (-)	768	WP_003058809.1	LexA family transcriptional regulator	Regulator
M28_RS09190 (M28_Spy1792)	-	1810648..1810854 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
M28_RS09195 (M28_Spy1793)	-	1810888..1811088 (+)	201	WP_002992502.1	helix-turn-helix domain-containing protein	-
M28_RS09200 (M28_Spy1794)	-	1811109..1811516 (+)	408	WP_002992501.1	hypothetical protein	-
M28_RS09990 (M28_Spy1795)	-	1811529..1811651 (+)	123	WP_011285272.1	hypothetical protein	-
M28_RS09205 (M28_Spy1796)	-	1811934..1812455 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
M28_RS09210 (M28_Spy1797)	-	1812703..1812876 (+)	174	WP_000132665.1	hypothetical protein	-
M28_RS09215 (M28_Spy1798)	-	1813094..1813267 (+)	174	WP_000074663.1	plasmid mobilization protein	-
M28_RS09220 (M28_Spy1799)	-	1813429..1813860 (+)	432	WP_136302445.1	hypothetical protein	-
M28_RS09225 (M28_Spy1800)	-	1813962..1814294 (+)	333	WP_011285276.1	hypothetical protein	-
M28_RS09230 (M28_Spy1801)	-	1814294..1814485 (+)	192	WP_021340709.1	hypothetical protein	-
M28_RS09235 (M28_Spy1802)	-	1814497..1814826 (+)	330	WP_003058810.1	hypothetical protein	-
M28_RS09240 (M28_Spy1803)	-	1814829..1815101 (+)	273	WP_010922766.1	hypothetical protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=24745 M28_RS09185 WP_003058809.1 1809727..1810494(-) (irvR) [Streptococcus pyogenes MGAS6180]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=24745 M28_RS09185 WP_003058809.1 1809727..1810494(-) (irvR) [Streptococcus pyogenes MGAS6180]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4