Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   CO204_RS03895 Genome accession   NZ_CP023477
Coordinates   746141..747034 (-) Length   297 a.a.
NCBI ID   WP_002272311.1    Uniprot ID   -
Organism   Streptococcus mutans strain LAR01     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 741141..752034
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO204_RS03875 (CO204_03865) cas2 741814..742158 (+) 345 WP_002263547.1 CRISPR-associated endonuclease Cas2 -
  CO204_RS03880 (CO204_03870) csn2 742148..742810 (+) 663 WP_002280936.1 type II-A CRISPR-associated protein Csn2 -
  CO204_RS03885 (CO204_03875) - 742907..743098 (+) 192 WP_002265423.1 type II toxin-antitoxin system HicA family toxin -
  CO204_RS03890 (CO204_03880) - 743116..743493 (+) 378 WP_002264915.1 type II toxin-antitoxin system HicB family antitoxin -
  CO204_RS03895 (CO204_03885) irvR 746141..747034 (-) 894 WP_002272311.1 LexA family transcriptional regulator IrvR Regulator
  CO204_RS03900 (CO204_03890) - 747350..747634 (+) 285 WP_002262720.1 helix-turn-helix transcriptional regulator -
  CO204_RS03905 (CO204_03895) - 747797..749548 (+) 1752 WP_106006714.1 GbpC/Spa domain-containing protein -
  CO204_RS10830 (CO204_03900) - 749678..749914 (+) 237 WP_032527746.1 hypothetical protein -
  CO204_RS10925 (CO204_03905) - 749949..750077 (+) 129 WP_002268967.1 hypothetical protein -

Sequence

Protein


Download         Length: 297 a.a.        Molecular weight: 33625.32 Da        Isoelectric Point: 6.7036

>NTDB_id=247418 CO204_RS03895 WP_002272311.1 746141..747034(-) (irvR) [Streptococcus mutans strain LAR01]
MGRGKLTPQDLEAMKAISANLQRLLAESGMKQSHLATILNIPTSSLNEYVKGKSLPKIGNIQKIADYFGLQKSDIDPRFA
SKKDSSTLDKINHIAKQLEMKRQIKVLDFCYQQSKEQDETASLSASDETTDDKVADKSNHTQYQKVVDSFIAKELNDQTI
IHWDNVIKAKDLYQTFGRQYENIQIYGEVSAGTGIWVGHEKQETIKYPIPIPEHDIALTVNGNSMEPLFYNGDVIFVKKT
KAIHHGQIIVVIVNNEAYVKKLYRKNKEIRLISLNPDYDDIILKEDDTIEVIGTVIT

Nucleotide


Download         Length: 894 bp        

>NTDB_id=247418 CO204_RS03895 WP_002272311.1 746141..747034(-) (irvR) [Streptococcus mutans strain LAR01]
ATGGGACGCGGTAAATTAACTCCACAAGATTTAGAAGCAATGAAGGCTATTTCTGCCAATCTTCAAAGACTTCTAGCTGA
GAGCGGAATGAAACAATCTCACTTAGCCACTATCCTTAACATTCCTACAAGTAGTCTTAATGAATATGTTAAAGGAAAGA
GTTTGCCAAAAATAGGGAATATTCAAAAAATCGCAGATTACTTTGGTCTCCAAAAATCCGATATTGACCCTAGATTTGCA
AGTAAAAAGGACTCTTCTACTCTTGATAAAATTAATCATATTGCCAAACAATTAGAAATGAAGAGACAGATAAAAGTCTT
AGATTTCTGTTACCAACAATCAAAGGAACAAGATGAAACAGCAAGCTTATCTGCCAGTGATGAAACGACTGATGATAAAG
TTGCTGACAAATCAAATCATACGCAGTATCAAAAGGTTGTTGATTCTTTTATTGCCAAAGAATTAAACGATCAGACAATT
ATTCATTGGGATAATGTGATAAAAGCTAAGGATTTGTATCAAACCTTTGGACGTCAATACGAAAACATTCAGATTTATGG
TGAAGTTTCAGCTGGTACTGGTATCTGGGTTGGACATGAAAAACAAGAAACCATTAAATACCCAATACCAATTCCAGAAC
ATGATATTGCTCTTACTGTCAATGGTAATAGTATGGAACCTTTATTTTACAACGGTGACGTTATTTTTGTTAAAAAGACT
AAAGCTATCCATCACGGACAAATTATCGTTGTTATTGTAAATAATGAGGCATATGTCAAAAAACTCTACCGAAAAAACAA
AGAAATTCGACTCATCTCATTAAATCCAGATTATGATGACATCATTTTAAAAGAAGATGATACAATTGAAGTCATCGGAA
CGGTCATTACCTAA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(22-70)

Peptidase S24-like (Peptidase_S24)

(184-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

99.327

100

0.993

Multiple sequence alignment