Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   M28_RS03790 Genome accession   NC_007296
Coordinates   737747..738223 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes MGAS6180     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 732747..743223
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M28_RS03765 (M28_Spy0712) - 732787..733575 (+) 789 WP_021340967.1 Nif3-like dinuclear metal center hexameric protein -
  M28_RS03770 (M28_Spy0713) - 733615..734721 (+) 1107 WP_011284727.1 NAD(P)/FAD-dependent oxidoreductase -
  M28_RS03775 (M28_Spy0714) rfbA 734780..735649 (+) 870 WP_011284728.1 glucose-1-phosphate thymidylyltransferase RfbA -
  M28_RS03780 (M28_Spy0715) - 735649..736242 (+) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  M28_RS03785 (M28_Spy0716) rfbB 736486..737526 (+) 1041 WP_011284729.1 dTDP-glucose 4,6-dehydratase -
  M28_RS03790 (M28_Spy0717) mutX 737747..738223 (+) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  M28_RS03795 (M28_Spy0718) - 738281..739462 (+) 1182 WP_011284730.1 AI-2E family transporter -
  M28_RS03800 (M28_Spy0719) - 739452..740699 (+) 1248 WP_002990000.1 tetratricopeptide repeat protein -
  M28_RS03805 (M28_Spy0720) fbp54 740758..742410 (-) 1653 WP_002991968.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=24696 M28_RS03790 WP_002984880.1 737747..738223(+) (mutX) [Streptococcus pyogenes MGAS6180]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=24696 M28_RS03790 WP_002984880.1 737747..738223(+) (mutX) [Streptococcus pyogenes MGAS6180]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703

Multiple sequence alignment