Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   CMR26_RS11015 Genome accession   NZ_CP023414
Coordinates   2260545..2261201 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain BS-37     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2255545..2266201
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CMR26_RS11000 (CMR26_11020) spxH 2255785..2256687 (+) 903 WP_007409106.1 protease adaptor protein SpxH -
  CMR26_RS20200 (CMR26_11025) - 2256973..2257140 (+) 168 WP_003155026.1 hypothetical protein -
  CMR26_RS11005 (CMR26_11030) pepF 2257178..2259007 (-) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  CMR26_RS11010 (CMR26_11035) - 2259235..2260395 (-) 1161 WP_007409108.1 competence protein CoiA family protein -
  CMR26_RS11015 (CMR26_11040) mecA 2260545..2261201 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  CMR26_RS20205 - 2261184..2261294 (-) 111 Protein_2152 adaptor protein MecA -
  CMR26_RS11020 (CMR26_11045) - 2261477..2262133 (+) 657 WP_108725048.1 TerC family protein -
  CMR26_RS11025 (CMR26_11050) spx 2262191..2262586 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  CMR26_RS11030 (CMR26_11055) - 2262765..2263343 (-) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  CMR26_RS11035 (CMR26_11060) - 2263461..2264648 (-) 1188 WP_053104215.1 putative glycoside hydrolase -
  CMR26_RS11040 (CMR26_11065) oppF 2264755..2265672 (-) 918 WP_108725049.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=246889 CMR26_RS11015 WP_003155032.1 2260545..2261201(-) (mecA) [Bacillus velezensis strain BS-37]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=246889 CMR26_RS11015 WP_003155032.1 2260545..2261201(-) (mecA) [Bacillus velezensis strain BS-37]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment