Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   TBD_RS11885 Genome accession   NC_007404
Coordinates   2442789..2444012 (-) Length   407 a.a.
NCBI ID   WP_011312881.1    Uniprot ID   Q3SGC8
Organism   Thiobacillus denitrificans ATCC 25259     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2437789..2449012
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TBD_RS11855 (Tbd_2363) ilvA 2438064..2439581 (-) 1518 WP_011312875.1 threonine ammonia-lyase, biosynthetic -
  TBD_RS11860 (Tbd_2364) rpiA 2439662..2440318 (+) 657 WP_011312876.1 ribose-5-phosphate isomerase RpiA -
  TBD_RS11865 (Tbd_2365) - 2440319..2440528 (-) 210 WP_011312877.1 DNA gyrase inhibitor YacG -
  TBD_RS11870 (Tbd_2366) zapD 2440525..2441280 (-) 756 WP_011312878.1 cell division protein ZapD -
  TBD_RS11875 (Tbd_2367) coaE 2441333..2441941 (-) 609 WP_011312879.1 dephospho-CoA kinase -
  TBD_RS11880 (Tbd_2368) pilD 2441941..2442792 (-) 852 WP_011312880.1 prepilin peptidase Machinery gene
  TBD_RS11885 (Tbd_2369) pilC 2442789..2444012 (-) 1224 WP_011312881.1 type II secretion system F family protein Machinery gene
  TBD_RS11890 (Tbd_2370) pilB 2444025..2445740 (-) 1716 WP_011312882.1 type IV-A pilus assembly ATPase PilB Machinery gene
  TBD_RS11895 (Tbd_2371) - 2445838..2447136 (-) 1299 WP_011312883.1 HlyC/CorC family transporter -
  TBD_RS11900 (Tbd_2372) ccsA 2447148..2447936 (-) 789 WP_011312884.1 cytochrome C assembly family protein -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 44019.11 Da        Isoelectric Point: 10.1240

>NTDB_id=24677 TBD_RS11885 WP_011312881.1 2442789..2444012(-) (pilC) [Thiobacillus denitrificans ATCC 25259]
MATAAKAVKDATFLWEGMDKRGKKVKGQIQAAGETLVNAQLRKQGIRVTKLKKQSNLFGGGKRITEKDVALFTRQLATMM
KAGVPLLQSFEIVARGHSNPSMQRLLMEIKADIEKGSSLTQSFARHPLYFDALFCNLVGAGEAAGILEAVLDRLAVYKEK
ILAIKGKIKSALFYPVSIIVVAFVITAIIMIFVIPAFKELFSSFGTDLPGPTLVVMAISDFFVTWWWAIFGGIGGGIYAF
LQAWKRSRKIQIAMDRFLLKLPIFGAVIEKATIARWTRTLSTMFAAGVPLVEALESVAGASGNQVFVEATQKIRGEVATG
TALTVAMQNSGRFPNMVLQMAAIGEESGSLDAMLGKVADFYESEVDDAVEALSSLMEPLIMVVLGTLIGGMVIAMYLPIF
KMGAVVG

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=24677 TBD_RS11885 WP_011312881.1 2442789..2444012(-) (pilC) [Thiobacillus denitrificans ATCC 25259]
ATGGCGACAGCGGCAAAGGCAGTCAAGGACGCGACCTTCCTGTGGGAAGGCATGGACAAGCGCGGCAAGAAGGTCAAGGG
TCAGATCCAGGCCGCCGGCGAAACGCTTGTCAACGCGCAGCTACGCAAGCAGGGGATCCGGGTCACGAAGCTCAAGAAGC
AGAGCAATCTTTTCGGCGGCGGCAAGCGCATCACCGAAAAGGATGTCGCGCTCTTCACGCGGCAGCTCGCGACCATGATG
AAGGCCGGCGTGCCCTTGCTGCAGTCGTTCGAAATCGTGGCCCGCGGGCACTCCAACCCGTCAATGCAGCGGCTGCTCAT
GGAGATCAAGGCCGACATCGAGAAGGGCAGCAGCCTCACGCAGTCGTTTGCACGGCACCCGCTCTATTTCGACGCACTCT
TCTGCAACCTCGTCGGGGCCGGCGAGGCGGCCGGTATCCTCGAGGCGGTGCTCGACCGGCTCGCGGTCTACAAGGAAAAG
ATCCTCGCGATCAAGGGCAAGATCAAGTCGGCGCTGTTCTACCCGGTGTCGATCATCGTGGTCGCCTTCGTCATCACGGC
GATCATCATGATTTTCGTCATCCCCGCCTTCAAGGAGCTATTCAGCAGCTTCGGGACGGACCTGCCGGGACCGACCCTGG
TCGTGATGGCGATTTCGGACTTTTTCGTCACGTGGTGGTGGGCGATTTTCGGCGGAATAGGCGGCGGCATCTACGCGTTT
CTGCAGGCGTGGAAGCGCTCGCGCAAGATCCAGATAGCCATGGACCGATTCTTGCTAAAGTTGCCCATTTTCGGCGCGGT
CATTGAAAAAGCGACGATCGCGCGCTGGACGCGCACGCTATCGACCATGTTCGCGGCAGGCGTACCGCTGGTCGAGGCAC
TCGAATCGGTTGCCGGCGCGTCGGGCAATCAGGTCTTCGTCGAGGCGACGCAGAAGATCCGCGGTGAGGTTGCGACCGGG
ACGGCCCTGACCGTCGCGATGCAGAACTCGGGGCGCTTTCCGAATATGGTGCTGCAGATGGCGGCGATCGGCGAGGAGTC
GGGCTCGCTCGACGCGATGCTCGGCAAGGTCGCCGATTTTTACGAGTCTGAAGTCGATGACGCCGTCGAGGCGCTGTCGA
GCCTGATGGAGCCCCTCATCATGGTCGTGTTGGGCACGCTGATCGGTGGGATGGTCATCGCGATGTACCTGCCGATCTTC
AAGATGGGCGCGGTCGTCGGATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3SGC8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

54.408

97.543

0.531
  pilC Acinetobacter baumannii D1279779

53.071

100

0.531
  pilC Pseudomonas stutzeri DSM 10701

53.218

99.263

0.528
  pilG Neisseria gonorrhoeae MS11

52.475

99.263

0.521
  pilG Neisseria meningitidis 44/76-A

51.98

99.263

0.516
  pilC Acinetobacter baylyi ADP1

52.645

97.543

0.514
  pilC Vibrio cholerae strain A1552

40.399

98.526

0.398
  pilC Vibrio campbellii strain DS40M4

38.741

100

0.393

Multiple sequence alignment