Detailed information NTG0246575

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CNH36_RS14810
• Genome accession: NZ_CP023391
• Coordinates: 2775182..2776069 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain Newman_D2C
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2770182..2781069

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CNH36_RS14775 (CNH36_14700)	-	2770201..2770293 (+)	93	WP_010956583.1	hypothetical protein	-
CNH36_RS14780 (CNH36_14705)	-	2770401..2770898 (-)	498	WP_001065268.1	glutathione peroxidase	-
CNH36_RS14785 (CNH36_14710)	-	2770908..2771168 (-)	261	WP_001789910.1	hypothetical protein	-
CNH36_RS14795 (CNH36_14720)	-	2771550..2771663 (-)	114	WP_011447078.1	hypothetical protein	-
CNH36_RS14800 (CNH36_14725)	-	2772322..2774322 (-)	2001	WP_000776751.1	ABC transporter permease	-
CNH36_RS14805 (CNH36_14730)	-	2774319..2775074 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
CNH36_RS14810 (CNH36_14735)	braS	2775182..2776069 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CNH36_RS14815 (CNH36_14740)	braR	2776080..2776745 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CNH36_RS14820 (CNH36_14745)	-	2776771..2776971 (-)	201	WP_000604728.1	hypothetical protein	-
CNH36_RS14825 (CNH36_14750)	-	2777169..2778593 (+)	1425	WP_000953744.1	alkaline phosphatase	-
CNH36_RS15555 (CNH36_14755)	-	2778653..2778754 (-)	102	WP_000731972.1	SE2200 family small protein	-
CNH36_RS14835 (CNH36_14760)	-	2778876..2779331 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
CNH36_RS14840 (CNH36_14765)	-	2779576..2780337 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=246575 CNH36_RS14810 WP_000143419.1 2775182..2776069(-) (braS) [Staphylococcus aureus strain Newman_D2C]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=246575 CNH36_RS14810 WP_000143419.1 2775182..2776069(-) (braS) [Staphylococcus aureus strain Newman_D2C]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997