Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   CMV18_RS14810 Genome accession   NZ_CP023341
Coordinates   2983979..2984635 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain LG37     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2978979..2989635
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CMV18_RS14795 (CMV18_14795) spxH 2979218..2980120 (+) 903 WP_032874464.1 protease adaptor protein SpxH -
  CMV18_RS19765 (CMV18_14800) - 2980406..2980573 (+) 168 WP_032874462.1 hypothetical protein -
  CMV18_RS14800 (CMV18_14805) pepF 2980611..2982440 (-) 1830 WP_087920792.1 oligoendopeptidase F Regulator
  CMV18_RS14805 (CMV18_14810) - 2982668..2983828 (-) 1161 WP_032874460.1 competence protein CoiA family protein -
  CMV18_RS14810 (CMV18_14815) mecA 2983979..2984635 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  CMV18_RS14815 (CMV18_14820) - 2984911..2985567 (+) 657 WP_032874459.1 TerC family protein -
  CMV18_RS14820 (CMV18_14825) spx 2985624..2986019 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  CMV18_RS14825 (CMV18_14830) - 2986198..2986776 (-) 579 WP_032874457.1 GNAT family N-acetyltransferase -
  CMV18_RS14830 (CMV18_14835) - 2986894..2988081 (-) 1188 WP_079891125.1 putative glycoside hydrolase -
  CMV18_RS14835 (CMV18_14840) oppF 2988188..2989105 (-) 918 WP_017417453.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=246175 CMV18_RS14810 WP_003155032.1 2983979..2984635(-) (mecA) [Bacillus velezensis strain LG37]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=246175 CMV18_RS14810 WP_003155032.1 2983979..2984635(-) (mecA) [Bacillus velezensis strain LG37]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATTAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAGA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment