Detailed information NTG0246132

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: CMV18_RS03740
• Genome accession: NZ_CP023341
• Coordinates: 703071..704234 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain LG37
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 698071..709234

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CMV18_RS03720 (CMV18_03710)	-	698511..699707 (+)	1197	WP_032876154.1	glycosyltransferase	-
CMV18_RS03725 (CMV18_03715)	-	699840..700916 (+)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
CMV18_RS03730 (CMV18_03720)	-	701015..702196 (-)	1182	WP_032876157.1	LCP family protein	-
CMV18_RS03735 (CMV18_03725)	-	702201..702848 (-)	648	WP_007614107.1	YigZ family protein	-
CMV18_RS03740 (CMV18_03730)	degS	703071..704234 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
CMV18_RS03745 (CMV18_03735)	degU	704311..705000 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
CMV18_RS03750 (CMV18_03740)	-	705098..705946 (+)	849	WP_032876160.1	DegV family protein	-
CMV18_RS03755 (CMV18_03745)	comFA	706055..707440 (+)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
CMV18_RS03760 (CMV18_03750)	-	707498..707782 (+)	285	WP_003151389.1	late competence development ComFB family protein	-
CMV18_RS03765 (CMV18_03755)	comFC	707788..708477 (+)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
CMV18_RS03770 (CMV18_03760)	-	708551..708970 (+)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=246132 CMV18_RS03740 WP_007407484.1 703071..704234(+) (degS) [Bacillus velezensis strain LG37]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=246132 CMV18_RS03740 WP_007407484.1 703071..704234(+) (degS) [Bacillus velezensis strain LG37]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951