Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   CLD04_RS06725 Genome accession   NZ_CP023257
Coordinates   1272414..1273070 (+) Length   218 a.a.
NCBI ID   WP_003232942.1    Uniprot ID   A0AAQ3ENL6
Organism   Bacillus subtilis strain TLO3     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1267414..1278070
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CLD04_RS06700 (CLD04_06700) oppF 1267668..1268585 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  CLD04_RS06705 (CLD04_06705) yjbB 1268691..1269908 (+) 1218 WP_095843630.1 MFS transporter -
  CLD04_RS06710 (CLD04_06710) yjbC 1270072..1270650 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  CLD04_RS06715 (CLD04_06715) spx 1270831..1271226 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  CLD04_RS06720 (CLD04_06720) yjbE 1271481..1272137 (-) 657 WP_003232944.1 TerC family protein -
  CLD04_RS21555 - 1272307..1272447 (+) 141 WP_119122854.1 hypothetical protein -
  CLD04_RS06725 (CLD04_06725) mecA 1272414..1273070 (+) 657 WP_003232942.1 adaptor protein MecA Regulator
  CLD04_RS21560 - 1273065..1273187 (-) 123 WP_003245684.1 hypothetical protein -
  CLD04_RS06730 (CLD04_06730) coiA 1273231..1274382 (+) 1152 WP_017695683.1 competence protein CoiA Machinery gene
  CLD04_RS06735 (CLD04_06735) pepF 1274612..1276441 (+) 1830 WP_171518460.1 oligoendopeptidase F -
  CLD04_RS06740 (CLD04_06740) - 1276479..1276646 (-) 168 WP_003244944.1 hypothetical protein -
  CLD04_RS06750 (CLD04_06750) spxH 1276961..1277860 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25762.62 Da        Isoelectric Point: 4.0841

>NTDB_id=245532 CLD04_RS06725 WP_003232942.1 1272414..1273070(+) (mecA) [Bacillus subtilis strain TLO3]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSNLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYANESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=245532 CLD04_RS06725 WP_003232942.1 1272414..1273070(+) (mecA) [Bacillus subtilis strain TLO3]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTTGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAATTTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAA
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.083

100

0.991

Multiple sequence alignment