Detailed information NTG0244846

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CJ017_RS09450
• Genome accession: NZ_CP023076
• Coordinates: 1931919..1932962 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus argenteus strain XNO62
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1926919..1937962

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CJ017_RS09420 (CJ017_09395)	-	1927330..1928577 (-)	1248	WP_000656301.1	aminopeptidase	-
CJ017_RS09425 (CJ017_09400)	-	1928589..1928789 (-)	201	WP_000180459.1	DUF1128 family protein	-
CJ017_RS09430 (CJ017_09405)	-	1928936..1929400 (+)	465	WP_000228669.1	low molecular weight protein-tyrosine-phosphatase	-
CJ017_RS09435 (CJ017_09410)	-	1929407..1929682 (+)	276	WP_000428174.1	YtxH domain-containing protein	-
CJ017_RS09440 (CJ017_09415)	-	1929961..1931184 (+)	1224	WP_000037065.1	YihY/virulence factor BrkB family protein	-
CJ017_RS09445 (CJ017_09420)	vraR	1931300..1931929 (-)	630	WP_000153529.1	two-component system response regulator VraR	Regulator
CJ017_RS09450 (CJ017_09425)	vraS	1931919..1932962 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
CJ017_RS09455 (CJ017_09430)	liaF	1932959..1933660 (-)	702	WP_031788217.1	cell wall-active antibiotics response protein LiaF	-
CJ017_RS09460 (CJ017_09435)	-	1933675..1934061 (-)	387	WP_001110170.1	hypothetical protein	-
CJ017_RS09465 (CJ017_09440)	map	1934282..1935040 (-)	759	WP_031788218.1	type I methionyl aminopeptidase	-
CJ017_RS09470 (CJ017_09445)	-	1935571..1936557 (+)	987	WP_031788370.1	FUSC family protein	-
CJ017_RS09480 (CJ017_09450)	-	1937189..1937911 (-)	723	WP_031787877.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=244846 CJ017_RS09450 WP_001017131.1 1931919..1932962(-) (vraS) [Staphylococcus argenteus strain XNO62]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=244846 CJ017_RS09450 WP_001017131.1 1931919..1932962(-) (vraS) [Staphylococcus argenteus strain XNO62]
ATGAACCATTATATTAGAACAATTGGTTCGATGCTCATCTTAGTATACAGCATGCTAGCGGCATTTCTTTTTATAGATAA
AGTTTTCGTTAATATTATTTATTTTCAAGGCATGTTTTATACACAAATATTTGGGATTCCAGTCTTTTTATTTTTAAATC
TCATTATCATTTTATTGTGTATCATCGTCGGATCGGTGCTTGCCTACAAAATTAATCAACAAAATGATTGGATTAAGACA
CAAATTGAGCGTTCTATGGAAGGCGAAACAGTAGGTATCAATGATCAAAATATAGAAATATATAGTGAAACATTAGATTT
ATATCATACGTTAGTACCTTTAAATCAAGAATTGCATAAGTTAAGACTCAAAACGCAAAATTTAACAAATGAAAATTACA
ATATTAATGATGTTAAAGTTAAAAAGATTATCGAAGATGAAAGACAACGTTTAGCTAGAGAACTACACGACTCTGTTAGT
CAACAACTTTTTGCGGCAAGTATGATGTTATCTGCAATTAAAGAAACGAAATTAGAACCACCTTTAGATCAACAAATACC
TATTTTAGAGAAAATGGTTCAAGATTCTCAGTTAGAAATGCGTGCTTTGCTGCTACACTTAAGACCACTCGGCTTGAAAG
ATAAGTCATTAGGCGAAGGTATTAAAGATTTAGTTATTGATTTACAAAAGAAAGTGCCAATGAAAGTTGTGCATGAGATA
CAAGATTTTAAAGTGCCAAAAGGTATTGAAGATCATTTATTTAGAATTACGCAAGAAGCAATATCTAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTAGAATTATTTAATAAAGATGATTATTTATTGTTAAGGATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCACTACCAGATTCAGGTACACGTATTGAGGTGAAAGCACCTCTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1