Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | M28_RS00695 | Genome accession | NC_007296 |
| Coordinates | 105283..106236 (+) | Length | 317 a.a. |
| NCBI ID | WP_010921802.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes MGAS6180 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 100283..111236
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M28_RS00655 (M28_Spy0083) | - | 101110..101475 (+) | 366 | WP_002986560.1 | DUF1033 family protein | - |
| M28_RS00660 (M28_Spy0084) | comYA | 101568..102506 (+) | 939 | WP_011284420.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| M28_RS00665 (M28_Spy0085) | comYB | 102442..103476 (+) | 1035 | WP_227868694.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| M28_RS00670 (M28_Spy0086) | comYC | 103478..103804 (+) | 327 | WP_002986552.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| M28_RS00675 (M28_Spy0087) | comGD | 103779..104207 (+) | 429 | WP_002986548.1 | competence type IV pilus minor pilin ComGD | - |
| M28_RS00680 (M28_Spy0088) | comGE | 104164..104448 (+) | 285 | WP_011284422.1 | competence type IV pilus minor pilin ComGE | - |
| M28_RS00685 (M28_Spy0089) | comYF | 104441..104875 (+) | 435 | WP_002992738.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| M28_RS00690 (M28_Spy0090) | comGG | 104859..105185 (+) | 327 | WP_010921801.1 | competence type IV pilus minor pilin ComGG | - |
| M28_RS00695 (M28_Spy0091) | comYH | 105283..106236 (+) | 954 | WP_010921802.1 | class I SAM-dependent methyltransferase | Machinery gene |
| M28_RS00700 (M28_Spy0092) | - | 106295..107491 (+) | 1197 | WP_011284424.1 | acetate kinase | - |
| M28_RS00705 (M28_Spy0093) | - | 107678..107986 (+) | 309 | WP_011284425.1 | hypothetical protein | - |
| M28_RS00710 (M28_Spy0094) | proC | 108069..108839 (-) | 771 | WP_011284426.1 | pyrroline-5-carboxylate reductase | - |
| M28_RS00715 (M28_Spy0095) | pepA | 108887..109954 (-) | 1068 | WP_011284427.1 | glutamyl aminopeptidase | - |
| M28_RS00725 (M28_Spy0097) | - | 110419..110703 (+) | 285 | WP_002992749.1 | DUF4651 domain-containing protein | - |
| M28_RS00730 (M28_Spy0098) | - | 110700..111017 (+) | 318 | WP_011284428.1 | thioredoxin family protein | - |
Sequence
Protein
Download Length: 317 a.a. Molecular weight: 36015.10 Da Isoelectric Point: 4.7205
>NTDB_id=24465 M28_RS00695 WP_010921802.1 105283..106236(+) (comYH) [Streptococcus pyogenes MGAS6180]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVTLITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
Nucleotide
Download Length: 954 bp
>NTDB_id=24465 M28_RS00695 WP_010921802.1 105283..106236(+) (comYH) [Streptococcus pyogenes MGAS6180]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACG
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGACCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACG
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGACCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
65.823 |
99.685 |
0.656 |
| comYH | Streptococcus mutans UA140 |
65.506 |
99.685 |
0.653 |