Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexA   Type   Machinery gene
Locus tag   STR_RS08035 Genome accession   NC_006449
Coordinates   1525864..1529517 (-) Length   1217 a.a.
NCBI ID   WP_011227531.1    Uniprot ID   Q5LY80
Organism   Streptococcus thermophilus CNRZ1066     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1520864..1534517
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STR_RS08015 (str1711) proB 1521215..1522018 (-) 804 WP_002948808.1 glutamate 5-kinase -
  STR_RS08020 (str1712) - 1522139..1523728 (-) 1590 WP_011226516.1 hypothetical protein -
  STR_RS08025 (str1713) - 1523731..1524463 (-) 733 Protein_1519 ABC transporter ATP-binding protein -
  STR_RS08030 (str1715) - 1524737..1525470 (+) 734 Protein_1520 DUF554 domain-containing protein -
  STR_RS08035 (str1716) rexA 1525864..1529517 (-) 3654 WP_011227531.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  STR_RS08040 (str1717) rexB 1529507..1532827 (-) 3321 WP_011227532.1 ATP-dependent nuclease subunit B Machinery gene
  STR_RS11700 (str1718) - 1533317..1533968 (-) 652 Protein_1523 hypothetical protein -
  STR_RS11705 - 1534021..1534451 (-) 431 Protein_1524 LytTR family DNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 1217 a.a.        Molecular weight: 138351.38 Da        Isoelectric Point: 4.7157

>NTDB_id=24391 STR_RS08035 WP_011227531.1 1525864..1529517(-) (rexA) [Streptococcus thermophilus CNRZ1066]
MLTKAFLSPAEIEERIAQEAASDKDRKLTPEQIEAIYSNGTNILVSASAGSGKTFVMVERILDMIGRGVGIDQLFISTFT
VKAAGELKERLEKRLTKHLGQAETDEERAFLSDQIAKIGTADIGTMDAFTQKLVNQYGYLLGVSPTFRIMTDLAEQTLMK
NEVYADLFNDYMQGKDAQLFQKLVRNFTGHSKTSKAFRDLVYDIYSFSQATADPEKWLCQNLLKGQIEAKPEQAKNELLD
GLKDGLLADFLAFLRDHLGIAQREFAKAKYLNNVSDAIILLEGSLINDQTDMEDLLKQLLTLSGGTGLTNMTRPKDEELK
AYKEAYNKTKNEFVAQLREVDTQLTVLEVLTKHNDDILPMLELLQSFVLDFSDQYLQAKIQENTFEFSDIAHFAIRILEE
NPEVAVSYRDRYHEVMVDEYQDNSHTQERMLELLSNGHNRFMVGDIKQSIYRFRQADPQIFNDKFQLFLENPDAGKLILL
KENFRSQSEVLDATNGVFSHLMDQEIGDILYDKTHMLVAGSQKQKEPHPENETEVLIYNSDESSTSEDEEGPDQAISSGE
ISLVIKEIIKLHEQGVRFEDITLLAPNRNTYLDLMVSFEEHGIPLVPDEYKSSYLESLEVMIMLDTLRAINNPLNDYALV
ALLRSPMFNFNEDDLTRIAVQADKGQFYDKLLAAHTKSGLHPEVVMQGLEAKLTLFTETLADWRDYSKCHSIYDLIWKIY
NDRFYYDYVGGLPRAEQRQANLYALALRANAYEKTGFKGLSRFIGMIDKIIASGNDLEEVTDLVPKNAVSLMTIHKSKGL
EFKYVFVLQMNRKFIGHSKDGLSGKYIINREKGLGIKYLADLKDQINTNLPKLNVVLETLTFQDNRREERRASISEEMRL
LYVAMTRAEKKLYLVGKGSKETLTQQYGTDVENNRLPVALRDQIATYQDWIMALDTAFMRKDLKFTVRFVEDEELTPEAI
GQVEVKAAVDADDLSNNRQTEEIERALTVLESVEKLNHLYAPAIDLPSVRTPSQLKTFYEPIMDTEGVDIMDKKEGVQPL
ETASTFELPDFGQKTKVTGAAVGSATHELMQRLTLSDTVTLQDLTQALSRVSASDQVKARVQLEKLLGFFDTELGKLILA
NRDKLRREAPFAMLAEDPASKEDFVVRGIIDGYLLLEDRIVLFDYKTDHFTHPSELKTRYQGQMSLYAKALSQAYQMEKV
DKYLILLGGKDLEVVEV

Nucleotide


Download         Length: 3654 bp        

>NTDB_id=24391 STR_RS08035 WP_011227531.1 1525864..1529517(-) (rexA) [Streptococcus thermophilus CNRZ1066]
ATGTTGACTAAAGCTTTTTTAAGTCCAGCAGAGATTGAGGAACGTATTGCCCAAGAAGCAGCTTCTGACAAGGATCGCAA
GTTAACACCAGAACAGATTGAAGCTATTTACAGTAATGGTACTAATATTTTGGTATCTGCCTCAGCTGGTTCAGGGAAAA
CCTTTGTCATGGTTGAGCGTATCCTTGATATGATTGGACGTGGCGTTGGTATTGATCAACTCTTTATCTCAACCTTTACG
GTAAAAGCTGCAGGTGAGTTAAAGGAGCGTCTGGAAAAGCGGCTGACAAAGCATTTAGGACAGGCAGAGACGGATGAGGA
GCGGGCATTTCTTTCAGACCAGATTGCCAAGATTGGGACGGCTGATATTGGAACCATGGATGCCTTTACCCAGAAATTGG
TCAATCAGTATGGCTATCTCCTGGGTGTGTCACCTACTTTCCGTATCATGACAGACCTTGCTGAGCAGACGCTTATGAAA
AATGAGGTTTATGCTGATCTCTTCAATGATTACATGCAAGGAAAGGATGCCCAACTTTTTCAAAAATTGGTCCGTAATTT
CACTGGACATAGCAAAACTAGCAAGGCTTTTCGTGATTTAGTTTACGATATTTACAGCTTTTCTCAGGCTACTGCAGATC
CTGAAAAATGGCTATGTCAAAATCTCTTGAAAGGACAGATCGAGGCTAAGCCAGAACAGGCTAAAAATGAGCTTTTAGAC
GGTCTCAAAGATGGCTTGTTGGCTGATTTCCTAGCTTTCTTAAGAGACCATTTAGGTATAGCTCAGCGTGAATTTGCCAA
GGCCAAGTATCTGAATAATGTGTCAGATGCCATTATCCTTCTTGAGGGCTCCTTGATTAATGACCAAACTGATATGGAGG
ACCTCCTCAAACAACTATTGACTCTGTCAGGAGGTACTGGTTTGACCAATATGACCCGTCCTAAAGACGAGGAACTCAAG
GCCTACAAGGAAGCATACAACAAGACCAAAAATGAGTTTGTGGCTCAGTTGCGAGAGGTCGATACTCAGCTCACCGTTCT
GGAGGTTTTGACCAAGCATAATGATGATATCCTACCTATGTTGGAGCTACTTCAGTCCTTTGTACTTGATTTTTCGGATC
AGTATTTACAGGCAAAGATTCAGGAAAATACCTTTGAATTCTCGGATATTGCCCACTTTGCTATCCGTATTTTGGAAGAA
AATCCAGAGGTGGCAGTCAGCTACCGGGACCGTTACCATGAAGTTATGGTGGATGAGTATCAGGACAATAGCCATACTCA
AGAACGAATGTTGGAACTTCTATCTAACGGCCATAACCGATTCATGGTGGGAGATATCAAGCAGTCCATTTATCGTTTCC
GTCAGGCAGACCCTCAGATTTTTAATGATAAGTTTCAGCTTTTCCTTGAAAATCCTGATGCAGGTAAGCTGATTCTCCTT
AAGGAGAACTTTCGTAGTCAATCTGAAGTCCTTGATGCGACAAATGGTGTTTTTAGCCACCTCATGGATCAGGAAATCGG
GGACATCCTATATGACAAGACTCATATGTTGGTAGCAGGTAGTCAGAAGCAAAAAGAGCCCCATCCTGAAAATGAAACTG
AGGTTCTGATTTATAATAGTGATGAATCTAGTACGAGTGAGGATGAAGAAGGTCCTGATCAAGCTATCAGCAGCGGTGAG
ATTTCCTTGGTTATCAAAGAAATTATCAAACTTCATGAGCAGGGTGTACGTTTTGAGGACATCACCCTCCTAGCACCGAA
CCGTAACACCTATCTGGACTTGATGGTAAGTTTCGAGGAACACGGGATTCCCTTGGTTCCTGACGAGTATAAGTCAAGCT
ACCTAGAGTCACTAGAAGTTATGATTATGTTGGACACCCTTCGTGCTATCAATAATCCTCTTAACGATTATGCTCTCGTT
GCTCTCCTTCGTTCACCTATGTTTAACTTCAACGAGGATGACCTGACTCGTATCGCAGTTCAGGCTGACAAAGGCCAATT
CTATGATAAGCTTCTTGCAGCTCATACCAAATCAGGTCTTCATCCGGAAGTTGTGATGCAAGGACTTGAAGCCAAGTTGA
CTCTCTTCACAGAGACTCTGGCAGATTGGCGTGACTACAGTAAGTGTCATTCGATTTATGACCTCATTTGGAAGATTTAC
AACGACCGTTTCTATTATGATTACGTCGGAGGTCTTCCACGAGCTGAGCAACGCCAGGCCAATCTTTATGCCCTTGCCTT
GCGTGCTAATGCTTATGAAAAGACAGGATTTAAGGGGCTTTCTCGTTTTATTGGCATGATTGATAAGATTATTGCTAGCG
GTAACGACCTAGAGGAAGTGACAGATTTGGTTCCCAAAAATGCCGTTAGCCTCATGACCATTCACAAGTCCAAGGGGCTA
GAGTTCAAGTATGTCTTTGTCCTGCAGATGAATCGCAAGTTCATTGGTCACAGCAAGGATGGCCTGAGCGGTAAGTATAT
TATCAATCGTGAAAAAGGGCTTGGTATTAAGTATCTAGCTGACCTCAAAGACCAGATAAACACCAATTTGCCTAAGTTAA
ATGTTGTTCTTGAGACCTTGACCTTCCAGGATAATCGTAGGGAAGAGCGCAGGGCAAGTATTTCAGAAGAGATGCGTCTA
CTCTATGTGGCAATGACACGTGCAGAGAAGAAACTCTACCTAGTTGGTAAGGGAAGTAAGGAAACCTTAACCCAGCAGTA
TGGCACTGATGTCGAAAATAATCGCCTACCAGTGGCTCTACGTGACCAGATTGCTACTTATCAGGATTGGATTATGGCAC
TTGATACTGCTTTTATGAGAAAAGACCTCAAGTTTACTGTTCGCTTTGTTGAGGATGAGGAGTTGACGCCAGAGGCTATT
GGACAGGTTGAAGTCAAGGCAGCAGTAGATGCCGATGATTTATCTAACAATCGTCAGACGGAGGAGATTGAGCGTGCCTT
GACTGTCTTAGAAAGTGTTGAAAAACTCAACCACCTTTATGCACCAGCGATTGACCTACCTTCTGTGCGTACCCCAAGCC
AGCTCAAGACCTTTTACGAACCAATTATGGATACAGAGGGCGTAGATATCATGGATAAGAAAGAGGGAGTGCAACCTCTT
GAGACGGCTAGCACTTTTGAGCTACCAGACTTTGGGCAAAAAACTAAGGTCACTGGAGCTGCAGTTGGTTCAGCAACCCA
TGAACTCATGCAACGCTTGACTCTTTCTGATACAGTGACTCTCCAAGATTTGACTCAGGCACTGAGTCGGGTATCGGCAT
CTGATCAAGTCAAGGCGCGTGTTCAGTTAGAAAAACTTTTAGGCTTCTTTGATACAGAGCTCGGGAAGCTTATTTTGGCC
AACCGTGATAAGTTGCGTCGTGAAGCACCTTTTGCCATGTTGGCAGAAGACCCAGCTAGTAAAGAAGACTTTGTTGTTCG
TGGAATCATTGATGGCTATCTTCTTCTTGAAGACCGTATTGTCCTCTTTGACTACAAGACCGACCACTTCACTCATCCTA
GTGAGCTTAAGACGCGCTACCAAGGGCAAATGAGCCTCTATGCTAAAGCGCTTAGCCAAGCCTATCAAATGGAAAAGGTC
GACAAATATCTTATCCTCTTGGGTGGAAAGGACTTAGAAGTTGTAGAAGTATAA

Domains

Predicted by InterProScan.

UvrD/REP helicase N-terminal domain (UvrD-helicase)

(28-464)

UvrD-like helicase C-terminal domain (UvrD_C)

(478-894)

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(1059-1198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5LY80

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexA Streptococcus pneumoniae R6

50.612

100

0.509

Multiple sequence alignment