Detailed information NTG0024387

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: STR_RS07745
• Genome accession: NC_006449
• Coordinates: 1468484..1469560 (-)
• Length: 358 a.a.
• NCBI ID: WP_011226464.1
• Uniprot ID: Q5M2Z4
• Organism: Streptococcus thermophilus CNRZ1066
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1463484..1474560

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STR_RS07725 (str1643)	-	1464596..1466662 (-)	2067	WP_011227498.1	cation:proton antiporter	-
STR_RS07730 (str1644)	-	1466671..1466913 (-)	243	WP_011227499.1	hypothetical protein	-
STR_RS07735 (str1645)	-	1466910..1467458 (-)	549	WP_004197152.1	tRNA (mnm(5)s(2)U34)-methyltransferase	-
STR_RS07740 (str1646)	-	1467455..1468399 (-)	945	WP_011226463.1	TIGR01212 family radical SAM protein	-
STR_RS07745 (str1647)	sepM	1468484..1469560 (-)	1077	WP_011226464.1	SepM family pheromone-processing serine protease	Regulator
STR_RS07750 (str1648)	coaD	1469538..1470035 (-)	498	WP_011226465.1	pantetheine-phosphate adenylyltransferase	-
STR_RS07755 (str1649)	rsmD	1470069..1470668 (-)	600	WP_011227500.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
STR_RS07760 (str1650)	trxB	1470759..1471712 (-)	954	WP_255136104.1	thioredoxin-disulfide reductase	-
STR_RS07765 (str1651)	-	1471745..1471969 (-)	225	WP_011227501.1	DUF4059 family protein	-
STR_RS07770 (str1652)	amiE	1472184..1472927 (-)	744	WP_011226469.1	amino acid ABC transporter ATP-binding protein	Regulator
STR_RS07775 (str1653)	-	1472927..1473673 (-)	747	WP_095559509.1	amino acid ABC transporter permease	-

Sequence

Protein

• Length: 358 a.a.
• Molecular weight: 39232.11 Da
• Isoelectric Point: 9.4944

>NTDB_id=24387 STR_RS07745 WP_011226464.1 1468484..1469560(-) (sepM) [Streptococcus thermophilus CNRZ1066]
MANKTKSKSLLEKMWRIKWWLLSIFTVLFLLFALFFPLNNYYVELPGGAFDTKEVLTVNKKADDSKGSYNFVAVAQTKAT
LALMLYTQFNDFAKLQTAEEATGNYSDEDFMRINQFYMETSQNQAVYQGLTLAGKEVSLEYMGVYVLQVADDSSFKGVLN
IADTVTAVNGKTFDNSTDMIKYVQGLKLGSKVKVTYMRDGKEKTATGKIIKIANGKNGIGIGLTDHTEIKSPENVKFKLD
GVGGPSAGLMFTLAIYDQVSGQDLKAGRKIAGTGTIEKDGAVGDIGGAYLKVKSAADSGADIFFVPNNLVTKEMKKADPD
AKTNYQEAKEAAEKLGTKMKIVPVKTAQEAIDYLKKTK

Nucleotide

• Length: 1077 bp

>NTDB_id=24387 STR_RS07745 WP_011226464.1 1468484..1469560(-) (sepM) [Streptococcus thermophilus CNRZ1066]
GTGGCAAACAAGACAAAATCTAAATCGCTATTAGAGAAAATGTGGCGTATTAAGTGGTGGTTATTAAGTATTTTTACGGT
ACTTTTCCTCCTTTTTGCCCTCTTTTTCCCGCTCAATAATTACTATGTGGAGCTTCCGGGTGGTGCTTTTGATACCAAGG
AAGTCTTGACAGTGAATAAGAAAGCTGATGATTCTAAGGGCTCCTATAATTTTGTGGCGGTGGCTCAAACCAAGGCGACT
TTGGCCTTGATGCTCTATACTCAGTTTAATGATTTTGCAAAGCTTCAAACGGCTGAAGAGGCAACTGGAAATTACTCTGA
TGAAGATTTCATGCGCATCAACCAATTTTACATGGAGACTTCTCAAAACCAAGCGGTTTATCAGGGCTTGACTCTGGCTG
GTAAGGAGGTTAGTTTGGAGTATATGGGTGTCTATGTGCTTCAGGTTGCTGATGATTCTAGCTTCAAGGGTGTCCTCAAT
ATTGCTGATACGGTGACGGCTGTTAATGGTAAGACCTTTGATAATTCTACTGACATGATTAAATACGTTCAAGGACTTAA
GCTGGGTTCAAAGGTCAAGGTCACTTATATGAGAGATGGCAAAGAAAAGACTGCTACTGGTAAGATTATTAAGATTGCCA
ATGGCAAAAATGGTATTGGTATCGGCCTAACGGACCATACTGAGATCAAGAGTCCTGAGAATGTTAAGTTTAAACTGGAT
GGTGTCGGTGGGCCAAGTGCTGGTCTTATGTTTACCTTGGCTATTTACGATCAGGTGTCTGGTCAAGACCTCAAGGCTGG
CCGCAAGATTGCTGGTACAGGAACTATTGAAAAAGATGGGGCTGTCGGTGATATCGGTGGGGCCTATCTCAAGGTGAAAT
CTGCGGCTGATAGTGGCGCAGACATTTTCTTCGTGCCAAATAATCTAGTAACTAAGGAAATGAAAAAGGCTGATCCGGAT
GCCAAGACTAATTATCAAGAGGCCAAGGAAGCTGCCGAGAAACTGGGGACCAAGATGAAAATCGTCCCTGTTAAAACAGC
TCAAGAAGCCATTGATTATTTGAAAAAGACTAAATGA

Domains

Predicted by InterProScan.

• PDZ domain (PDZ_2) (137-206)

3D structure

• AlphaFold DB: Q5M2Z4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	62.757	95.251	0.598