Detailed information    

insolico Bioinformatically predicted

Overview

Name   comO   Type   Machinery gene
Locus tag   NTHI_RS05330 Genome accession   NC_007146
Coordinates   1057432..1058151 (+) Length   239 a.a.
NCBI ID   WP_011272300.1    Uniprot ID   Q4QLW9
Organism   Haemophilus influenzae 86-028NP     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1052432..1063151
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NTHI_RS05310 (NTHI1106) - 1053362..1053892 (-) 531 WP_005688388.1 DsbE family thiol:disulfide interchange protein -
  NTHI_RS05315 (NTHI1107) nrfE 1053892..1055799 (-) 1908 WP_011272297.1 heme lyase NrfEFG subunit NrfE -
  NTHI_RS05320 (NTHI1108) suhB 1055908..1056720 (-) 813 WP_011272298.1 inositol-1-monophosphatase -
  NTHI_RS05325 (NTHI1109) comN 1056920..1057432 (+) 513 WP_011272299.1 pilus assembly FimT family protein Machinery gene
  NTHI_RS05330 (NTHI1110) comO 1057432..1058151 (+) 720 WP_011272300.1 PulJ/GspJ family protein Machinery gene
  NTHI_RS05335 (NTHI1111) comP 1058148..1058831 (+) 684 WP_011272301.1 DUF2572 family protein Machinery gene
  NTHI_RS05340 (NTHI1112) comQ 1058824..1059111 (+) 288 WP_021034778.1 DUF5374 domain-containing protein Machinery gene
  NTHI_RS05345 (NTHI1113) recC 1059157..1062522 (+) 3366 WP_011272303.1 exodeoxyribonuclease V subunit gamma -
  NTHI_RS05350 (NTHI1114) nrdR 1062577..1063026 (+) 450 WP_005648026.1 transcriptional regulator NrdR -

Sequence

Protein


Download         Length: 239 a.a.        Molecular weight: 26922.29 Da        Isoelectric Point: 9.3761

>NTDB_id=24379 NTHI_RS05330 WP_011272300.1 1057432..1058151(+) (comO) [Haemophilus influenzae 86-028NP]
MMKTLLKGQTLLALMISLALSSLLLLSISHFYVQIQTQNQQMLLHLKLQAELQRILQLIGKDLRRLGFRALNAKLTESNL
FLFELDEQGTAIFISQEDNAPPNSCVLFFYDLNKNGCIGKGSPKTCMKNGKNTSKSSTEELFGYKVSNKMIKTKLTYQSV
IPTNCTAETCKRAFQQTACNAGGGWADLLDNNEYEITRLQFNWLIEGKGLEIKLKGNLKQTPNISYETSLVVALWNQKQ

Nucleotide


Download         Length: 720 bp        

>NTDB_id=24379 NTHI_RS05330 WP_011272300.1 1057432..1058151(+) (comO) [Haemophilus influenzae 86-028NP]
ATGATGAAAACATTATTAAAAGGGCAAACCCTATTAGCACTGATGATTTCACTGGCTTTGTCTTCTTTATTGCTGCTAAG
CATTTCGCATTTTTATGTGCAAATACAAACACAAAACCAACAAATGTTATTACATTTAAAATTACAAGCTGAATTACAAC
GAATATTACAGTTAATAGGCAAAGATCTTCGCCGATTAGGATTTCGAGCATTAAATGCAAAACTGACGGAAAGCAATTTA
TTTTTATTTGAATTAGATGAACAAGGCACAGCCATTTTTATTAGCCAAGAAGATAATGCGCCACCTAATAGCTGCGTGTT
GTTCTTTTATGATTTAAATAAAAATGGGTGTATTGGTAAAGGTTCGCCGAAAACCTGTATGAAAAATGGGAAAAATACAT
CTAAAAGTAGTACTGAAGAATTATTTGGCTATAAAGTGAGTAACAAAATGATAAAAACCAAACTGACTTATCAAAGTGTT
ATTCCTACTAATTGCACGGCAGAAACGTGTAAACGTGCTTTTCAACAAACCGCTTGCAACGCTGGGGGAGGTTGGGCAGA
TTTATTAGATAACAACGAATATGAAATTACTAGGCTACAATTTAATTGGTTAATTGAAGGCAAAGGATTAGAAATCAAGT
TAAAAGGAAATTTAAAACAAACCCCAAATATCAGTTATGAAACCTCCCTTGTCGTTGCTCTTTGGAATCAAAAACAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLW9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comO Haemophilus influenzae Rd KW20

97.059

99.582

0.967

Multiple sequence alignment