Detailed information NTG0024375

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: STR_RS06765
• Genome accession: NC_006449
• Coordinates: 1278627..1279712 (-)
• Length: 361 a.a.
• NCBI ID: WP_011226304.1
• Uniprot ID: Q5M3H6
• Organism: Streptococcus thermophilus CNRZ1066
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1273627..1284712

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STR_RS06735 (str1433)	-	1273993..1274808 (-)	816	WP_011227405.1	Cof-type HAD-IIB family hydrolase	-
STR_RS06740 (str1434)	-	1274801..1275595 (-)	795	WP_011227406.1	HAD hydrolase family protein	-
STR_RS06745 (str1435)	-	1275778..1276155 (+)	378	WP_011226300.1	GntR family transcriptional regulator	-
STR_RS06750 (str1436)	-	1276160..1276858 (+)	699	WP_011226301.1	ABC transporter ATP-binding protein	-
STR_RS06755 (str1437)	-	1276870..1277655 (+)	786	WP_002951425.1	hypothetical protein	-
STR_RS06760 (str1438)	-	1277705..1278634 (-)	930	WP_002951426.1	ATP-binding cassette domain-containing protein	-
STR_RS06765 (str1439)	amiE	1278627..1279712 (-)	1086	WP_011226304.1	ABC transporter ATP-binding protein	Regulator
STR_RS06770 (str1440)	amiD	1279722..1280648 (-)	927	WP_002946409.1	oligopeptide ABC transporter permease OppC	Regulator
STR_RS06775 (str1441)	amiC	1280648..1282141 (-)	1494	WP_011227407.1	ABC transporter permease	Regulator
STR_RS06780	-	1282203..1284169 (-)	1967	Protein_1271	peptide ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39864.62 Da
• Isoelectric Point: 4.7435

>NTDB_id=24375 STR_RS06765 WP_011226304.1 1278627..1279712(-) (amiE) [Streptococcus thermophilus CNRZ1066]
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGKDL
TKFKSHQDWAAIRGAKIATIFQDPMTSLNPIKTIGSQIIEVIVKHQGKTAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDNGKLFSIPGTPPSLYTPVVGDAFALRSDYALQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVDKPAVIQNLHEKILANMGFAHLGDEEEGNA

Nucleotide

• Length: 1086 bp

>NTDB_id=24375 STR_RS06765 WP_011226304.1 1278627..1279712(-) (amiE) [Streptococcus thermophilus CNRZ1066]
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
TATTCGAGGGGTTTCTCTTGATTTAGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAGTCTGGTTCAGGAAAATCAGTCT
TGACTAAAACTTTTACAGGGATGCTGGAAGAAAATGGTCGTGTAGCTAGCGGATCTATCGACTACCGTGGCAAAGACTTG
ACTAAATTTAAGAGTCACCAAGATTGGGCAGCTATCCGTGGAGCTAAGATTGCAACTATTTTCCAAGATCCAATGACCAG
TCTTAACCCAATTAAGACTATCGGAAGTCAAATTATTGAAGTTATTGTTAAGCACCAAGGGAAAACAGCCAAGGAAGCTA
AAAAAATGGCAATTGATTACATGGACAAGGTTGGTATTCCAGATGCTGAAAAACGTTTCAATGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTTATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAACCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATTGACCTCTTGAAATCACTCAAAGAGGAGTATGGTTTCTCGGTCA
TTTTCATTACCCATGACCTTGGCGTCGTAGCAAGTATCGCGGACAAGGTTGCTGTCATGTATGCTGGCGAAATCATTGAA
TACGCAACTGTTGAGGAAATTTTCTATGAGCCTTGTCATCCATACACGTGGAGCTTGCTTTCAAGTCTGCCACAATTGGC
TGATGATAATGGAAAACTCTTCTCAATTCCAGGGACGCCACCATCACTTTATACACCAGTTGTTGGGGATGCCTTTGCCT
TGCGTTCAGATTATGCTTTGCAGATTGATTTTGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCGCCAAAAGTTGATAAACCTGCGGTTATCCAAAATCTACATGAAAAAATCCTAGCCAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-300)

3D structure

• AlphaFold DB: Q5M3H6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus thermophilus LMG 18311	100	100	1
amiE	Streptococcus thermophilus LMD-9	100	100	1
amiE	Streptococcus salivarius strain HSISS4	96.953	100	0.97
oppD	Streptococcus mutans UA159	54.441	96.676	0.526