Detailed information NTG0243384

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CGP88_RS14280
• Genome accession: NZ_CP022910
• Coordinates: 2703512..2704399 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 164
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2698512..2709399

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CGP88_RS14245	-	2698531..2698623 (+)	93	WP_010956583.1	hypothetical protein	-
CGP88_RS14250 (CGP88_02557)	-	2698731..2699228 (-)	498	WP_001065268.1	glutathione peroxidase	-
CGP88_RS14255	-	2699238..2699498 (-)	261	WP_001789910.1	hypothetical protein	-
CGP88_RS14265	-	2699880..2699993 (-)	114	WP_011447078.1	hypothetical protein	-
CGP88_RS14270 (CGP88_02558)	-	2700652..2702652 (-)	2001	WP_000776751.1	ABC transporter permease	-
CGP88_RS14275 (CGP88_02559)	-	2702649..2703404 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
CGP88_RS14280 (CGP88_02560)	braS	2703512..2704399 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CGP88_RS14285 (CGP88_02561)	braR	2704410..2705075 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CGP88_RS14290 (CGP88_02562)	-	2705101..2705301 (-)	201	WP_000604728.1	hypothetical protein	-
CGP88_RS14295 (CGP88_02563)	-	2705499..2706923 (+)	1425	WP_000953744.1	alkaline phosphatase	-
CGP88_RS14930	-	2706993..2707103 (+)	111	WP_001791296.1	hypothetical protein	-
CGP88_RS14305 (CGP88_02565)	-	2707206..2707661 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
CGP88_RS14310 (CGP88_02566)	-	2707906..2708667 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=243384 CGP88_RS14280 WP_000143419.1 2703512..2704399(-) (braS) [Staphylococcus aureus strain 164]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=243384 CGP88_RS14280 WP_000143419.1 2703512..2704399(-) (braS) [Staphylococcus aureus strain 164]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997