Detailed information NTG0243344

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CGQ00_RS15010
• Genome accession: NZ_CP022908
• Coordinates: 2812409..2813296 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 545
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2807409..2818296

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CGQ00_RS14975	-	2807428..2807520 (+)	93	WP_010956583.1	hypothetical protein	-
CGQ00_RS14980 (CGQ00_02714)	-	2807628..2808125 (-)	498	WP_001065268.1	glutathione peroxidase	-
CGQ00_RS14985	-	2808135..2808395 (-)	261	WP_001789910.1	hypothetical protein	-
CGQ00_RS14995	-	2808777..2808890 (-)	114	WP_011447078.1	hypothetical protein	-
CGQ00_RS15000 (CGQ00_02715)	-	2809549..2811549 (-)	2001	WP_000776751.1	ABC transporter permease	-
CGQ00_RS15005 (CGQ00_02716)	-	2811546..2812301 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
CGQ00_RS15010 (CGQ00_02717)	braS	2812409..2813296 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CGQ00_RS15015 (CGQ00_02718)	braR	2813307..2813972 (-)	666	WP_115276695.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CGQ00_RS15020 (CGQ00_02719)	-	2813998..2814198 (-)	201	WP_000604728.1	hypothetical protein	-
CGQ00_RS15025 (CGQ00_02720)	-	2814396..2815820 (+)	1425	WP_000953744.1	alkaline phosphatase	-
CGQ00_RS15995 (CGQ00_02721)	-	2815880..2815981 (-)	102	WP_000731972.1	SE2200 family small protein	-
CGQ00_RS15035 (CGQ00_02722)	-	2816103..2816558 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
CGQ00_RS15040 (CGQ00_02723)	-	2816803..2817564 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=243344 CGQ00_RS15010 WP_000143419.1 2812409..2813296(-) (braS) [Staphylococcus aureus strain 545]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=243344 CGQ00_RS15010 WP_000143419.1 2812409..2813296(-) (braS) [Staphylococcus aureus strain 545]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997