Detailed information NTG0243302

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CGP99_RS14695
• Genome accession: NZ_CP022906
• Coordinates: 2769860..2770747 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 546
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2764860..2775747

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CGP99_RS14660	-	2764879..2764971 (+)	93	WP_010956583.1	hypothetical protein	-
CGP99_RS14665 (CGP99_02624)	-	2765079..2765576 (-)	498	WP_001065268.1	glutathione peroxidase	-
CGP99_RS14670	-	2765586..2765846 (-)	261	WP_001789910.1	hypothetical protein	-
CGP99_RS14680	-	2766228..2766341 (-)	114	WP_011447078.1	hypothetical protein	-
CGP99_RS14685 (CGP99_02625)	-	2767000..2769000 (-)	2001	WP_000776751.1	ABC transporter permease	-
CGP99_RS14690 (CGP99_02626)	-	2768997..2769752 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
CGP99_RS14695 (CGP99_02627)	braS	2769860..2770747 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CGP99_RS14700 (CGP99_02628)	braR	2770758..2771423 (-)	666	WP_115276695.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CGP99_RS14705 (CGP99_02629)	-	2771449..2771649 (-)	201	WP_000604728.1	hypothetical protein	-
CGP99_RS14710 (CGP99_02630)	-	2771847..2773271 (+)	1425	WP_000953744.1	alkaline phosphatase	-
CGP99_RS15485	-	2773341..2773451 (+)	111	WP_001791296.1	hypothetical protein	-
CGP99_RS14720 (CGP99_02632)	-	2773554..2774009 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
CGP99_RS14725 (CGP99_02633)	-	2774254..2775015 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=243302 CGP99_RS14695 WP_000143419.1 2769860..2770747(-) (braS) [Staphylococcus aureus strain 546]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=243302 CGP99_RS14695 WP_000143419.1 2769860..2770747(-) (braS) [Staphylococcus aureus strain 546]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997