Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   CGP99_RS11305 Genome accession   NZ_CP022906
Coordinates   2140054..2140770 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 546     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2135054..2145770
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGP99_RS15660 (CGP99_02030) - 2136310..2136444 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  CGP99_RS11275 (CGP99_02031) agrB 2136680..2137249 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  CGP99_RS11280 (CGP99_02032) - 2137246..2137386 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide -
  CGP99_RS11295 (CGP99_02034) - 2137680..2138852 (+) 1173 WP_000195429.1 IS256-like element IS256 family transposase -
  CGP99_RS11300 (CGP99_02035) - 2138902..2140035 (+) 1134 Protein_2088 GHKL domain-containing protein -
  CGP99_RS11305 (CGP99_02036) agrA 2140054..2140770 (+) 717 WP_000688492.1 LytTR family DNA-binding domain-containing protein Regulator
  CGP99_RS11310 - 2140842..2140949 (+) 108 WP_001790167.1 hypothetical protein -
  CGP99_RS11315 (CGP99_02037) - 2141137..2142096 (-) 960 WP_001253312.1 carbohydrate kinase -
  CGP99_RS11320 (CGP99_02038) - 2142093..2143577 (-) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  CGP99_RS11325 (CGP99_02039) - 2143726..2144676 (-) 951 WP_115276664.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=243298 CGP99_RS11305 WP_000688492.1 2140054..2140770(+) (agrA) [Staphylococcus aureus strain 546]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=243298 CGP99_RS11305 WP_000688492.1 2140054..2140770(+) (agrA) [Staphylococcus aureus strain 546]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment