Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGE   Type   Machinery gene
Locus tag   CGP99_RS08405 Genome accession   NZ_CP022906
Coordinates   1638054..1638353 (-) Length   99 a.a.
NCBI ID   WP_000844413.1    Uniprot ID   X5E258
Organism   Staphylococcus aureus strain 546     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 1636483..1637655 1638054..1638353 flank 399


Gene organization within MGE regions


Location: 1636483..1638353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGP99_RS08395 (CGP99_01521) - 1636483..1637655 (+) 1173 WP_000195429.1 IS256-like element IS256 family transposase -
  CGP99_RS08400 (CGP99_01522) comGF 1637639..1638136 (-) 498 WP_240316779.1 competence type IV pilus minor pilin ComGF Machinery gene
  CGP99_RS08405 (CGP99_01523) comGE 1638054..1638353 (-) 300 WP_000844413.1 hypothetical protein Machinery gene

Sequence


Protein


Download         Length: 99 a.a.        Molecular weight: 11093.20 Da        Isoelectric Point: 9.9215

>NTDB_id=243281 CGP99_RS08405 WP_000844413.1 1638054..1638353(-) (comGE) [Staphylococcus aureus strain 546]
MKSYKCKGSFLIDSMAGFLLIGLITLLLIPMMNQMQASINHKLQTIDASKVILTTVSKINKEELKKGVTIGKYDIKQSDQ
QICAISKNTTSYQKTCIQY

Nucleotide


Download         Length: 300 bp        

>NTDB_id=243281 CGP99_RS08405 WP_000844413.1 1638054..1638353(-) (comGE) [Staphylococcus aureus strain 546]
ATGAAAAGCTATAAGTGTAAAGGTTCATTCTTAATAGATAGTATGGCTGGATTTTTGCTAATTGGATTGATTACATTACT
ATTGATACCAATGATGAATCAAATGCAAGCGAGTATAAACCATAAACTACAAACAATTGATGCTTCTAAAGTAATTTTGA
CGACTGTATCTAAAATTAATAAAGAAGAACTTAAGAAGGGGGTAACTATAGGGAAGTATGATATTAAGCAAAGTGACCAA
CAAATTTGTGCTATTTCAAAAAATACCACTTCTTATCAAAAGACATGTATACAGTATTAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB X5E258

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Staphylococcus aureus MW2

86.842

100

1

  comGE Staphylococcus aureus N315

98.99

100

0.99


Multiple sequence alignment