Detailed information NTG0243164

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CGQ01_RS09195
• Genome accession: NZ_CP022903
• Coordinates: 1761273..1762316 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 187
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1756273..1767316

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CGQ01_RS09165 (CGQ01_01660)	-	1756694..1757950 (-)	1257	WP_001795108.1	aminopeptidase	-
CGQ01_RS09170 (CGQ01_01661)	-	1757953..1758153 (-)	201	WP_078066076.1	DUF1128 family protein	-
CGQ01_RS09175 (CGQ01_01662)	-	1758300..1758764 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
CGQ01_RS09180 (CGQ01_01663)	-	1758771..1759046 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
CGQ01_RS09185 (CGQ01_01664)	-	1759324..1760541 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
CGQ01_RS09190 (CGQ01_01665)	vraR	1760654..1761283 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
CGQ01_RS09195 (CGQ01_01666)	vraS	1761273..1762316 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
CGQ01_RS09200 (CGQ01_01667)	liaF	1762313..1763014 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
CGQ01_RS09205 (CGQ01_01668)	-	1763029..1763415 (-)	387	WP_001110179.1	hypothetical protein	-
CGQ01_RS09210 (CGQ01_01669)	map	1763632..1764390 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
CGQ01_RS09220 (CGQ01_01670)	-	1764921..1765907 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
CGQ01_RS09230 (CGQ01_01671)	-	1766338..1766751 (-)	414	WP_001557448.1	hypothetical protein	-
CGQ01_RS09235	-	1766780..1766890 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=243164 CGQ01_RS09195 WP_001017131.1 1761273..1762316(-) (vraS) [Staphylococcus aureus strain 187]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=243164 CGQ01_RS09195 WP_001017131.1 1761273..1762316(-) (vraS) [Staphylococcus aureus strain 187]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1