Detailed information NTG0243129

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CGP98_RS14690
• Genome accession: NZ_CP022902
• Coordinates: 2769853..2770740 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 165
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2764853..2775740

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CGP98_RS14655	-	2764872..2764964 (+)	93	WP_010956583.1	hypothetical protein	-
CGP98_RS14660 (CGP98_02623)	-	2765072..2765569 (-)	498	WP_001065268.1	glutathione peroxidase	-
CGP98_RS14665	-	2765579..2765839 (-)	261	WP_001789910.1	hypothetical protein	-
CGP98_RS14675	-	2766221..2766334 (-)	114	WP_011447078.1	hypothetical protein	-
CGP98_RS14680 (CGP98_02624)	-	2766993..2768993 (-)	2001	WP_000776751.1	ABC transporter permease	-
CGP98_RS14685 (CGP98_02625)	-	2768990..2769745 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
CGP98_RS14690 (CGP98_02626)	braS	2769853..2770740 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CGP98_RS14695 (CGP98_02627)	braR	2770751..2771416 (-)	666	WP_115276695.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CGP98_RS14700 (CGP98_02628)	-	2771442..2771642 (-)	201	WP_000604728.1	hypothetical protein	-
CGP98_RS14705 (CGP98_02629)	-	2771840..2773264 (+)	1425	WP_000953744.1	alkaline phosphatase	-
CGP98_RS15340	-	2773334..2773444 (+)	111	WP_001791296.1	hypothetical protein	-
CGP98_RS14715 (CGP98_02631)	-	2773547..2774002 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
CGP98_RS14720 (CGP98_02632)	-	2774247..2775008 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=243129 CGP98_RS14690 WP_000143419.1 2769853..2770740(-) (braS) [Staphylococcus aureus strain 165]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=243129 CGP98_RS14690 WP_000143419.1 2769853..2770740(-) (braS) [Staphylococcus aureus strain 165]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997