Detailed information NTG0242965

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CGP94_RS14160
• Genome accession: NZ_CP022898
• Coordinates: 2718418..2719305 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain 422
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2713418..2724305

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CGP94_RS14125	-	2713431..2713523 (+)	93	WP_010956583.1	hypothetical protein	-
CGP94_RS14130 (CGP94_02582)	-	2713631..2714128 (-)	498	WP_001065267.1	glutathione peroxidase	-
CGP94_RS14135 (CGP94_02583)	-	2714138..2714398 (-)	261	WP_014532715.1	hypothetical protein	-
CGP94_RS14145	-	2714780..2714893 (-)	114	WP_072357681.1	hypothetical protein	-
CGP94_RS14150 (CGP94_02584)	-	2715558..2717558 (-)	2001	WP_042907889.1	ABC transporter permease	-
CGP94_RS14155 (CGP94_02585)	-	2717555..2718310 (-)	756	WP_115385594.1	ABC transporter ATP-binding protein	-
CGP94_RS14160 (CGP94_02586)	braS	2718418..2719305 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CGP94_RS14165 (CGP94_02587)	braR	2719316..2719981 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CGP94_RS14170 (CGP94_02588)	-	2720007..2720207 (-)	201	WP_000604725.1	hypothetical protein	-
CGP94_RS14175 (CGP94_02589)	-	2720405..2721829 (+)	1425	WP_047213011.1	alkaline phosphatase	-
CGP94_RS14635	-	2721899..2722009 (+)	111	WP_001791296.1	hypothetical protein	-
CGP94_RS14185 (CGP94_02591)	-	2722112..2722567 (-)	456	WP_047213013.1	MarR family winged helix-turn-helix transcriptional regulator	-
CGP94_RS14190 (CGP94_02592)	-	2722812..2723573 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=242965 CGP94_RS14160 WP_000143420.1 2718418..2719305(-) (braS) [Staphylococcus aureus strain 422]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=242965 CGP94_RS14160 WP_000143420.1 2718418..2719305(-) (braS) [Staphylococcus aureus strain 422]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993