Detailed information NTG0242925

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CGP93_RS14160
• Genome accession: NZ_CP022897
• Coordinates: 2718420..2719307 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain 128
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2713420..2724307

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CGP93_RS14125	-	2713433..2713525 (+)	93	WP_010956583.1	hypothetical protein	-
CGP93_RS14130 (CGP93_02583)	-	2713633..2714130 (-)	498	WP_001065267.1	glutathione peroxidase	-
CGP93_RS14135 (CGP93_02584)	-	2714140..2714400 (-)	261	WP_014532715.1	hypothetical protein	-
CGP93_RS14145	-	2714782..2714895 (-)	114	WP_072357681.1	hypothetical protein	-
CGP93_RS14150 (CGP93_02585)	-	2715560..2717560 (-)	2001	WP_042907889.1	ABC transporter permease	-
CGP93_RS14155 (CGP93_02586)	-	2717557..2718312 (-)	756	WP_115385594.1	ABC transporter ATP-binding protein	-
CGP93_RS14160 (CGP93_02587)	braS	2718420..2719307 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CGP93_RS14165 (CGP93_02588)	braR	2719318..2719983 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CGP93_RS14170 (CGP93_02589)	-	2720009..2720209 (-)	201	WP_000604725.1	hypothetical protein	-
CGP93_RS14175 (CGP93_02590)	-	2720407..2721831 (+)	1425	WP_047213011.1	alkaline phosphatase	-
CGP93_RS14635	-	2721901..2722011 (+)	111	WP_001791296.1	hypothetical protein	-
CGP93_RS14185 (CGP93_02592)	-	2722114..2722569 (-)	456	WP_047213013.1	MarR family winged helix-turn-helix transcriptional regulator	-
CGP93_RS14190 (CGP93_02593)	-	2722814..2723575 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=242925 CGP93_RS14160 WP_000143420.1 2718420..2719307(-) (braS) [Staphylococcus aureus strain 128]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=242925 CGP93_RS14160 WP_000143420.1 2718420..2719307(-) (braS) [Staphylococcus aureus strain 128]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993