Detailed information NTG0242879

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CGP92_RS09890
• Genome accession: NZ_CP022896
• Coordinates: 1964653..1965696 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 277
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1959653..1970696

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CGP92_RS09860 (CGP92_01825)	-	1960074..1961330 (-)	1257	WP_001793983.1	aminopeptidase	-
CGP92_RS09865 (CGP92_01826)	-	1961333..1961533 (-)	201	WP_000180460.1	DUF1128 family protein	-
CGP92_RS09870 (CGP92_01827)	-	1961680..1962144 (+)	465	WP_000228670.1	low molecular weight protein-tyrosine-phosphatase	-
CGP92_RS09875 (CGP92_01828)	-	1962151..1962426 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
CGP92_RS09880 (CGP92_01829)	-	1962704..1963921 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
CGP92_RS09885 (CGP92_01830)	vraR	1964034..1964663 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
CGP92_RS09890 (CGP92_01831)	vraS	1964653..1965696 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
CGP92_RS09895 (CGP92_01832)	liaF	1965693..1966394 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
CGP92_RS09900 (CGP92_01833)	-	1966409..1966795 (-)	387	WP_001110178.1	hypothetical protein	-
CGP92_RS09905 (CGP92_01834)	map	1967012..1967770 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
CGP92_RS09925 (CGP92_01835)	-	1968470..1969456 (+)	987	WP_001014423.1	aromatic acid exporter family protein	-
CGP92_RS09930 (CGP92_01836)	-	1969645..1970058 (-)	414	WP_001643743.1	hypothetical protein	-
CGP92_RS09935	-	1970087..1970197 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=242879 CGP92_RS09890 WP_001017131.1 1964653..1965696(-) (vraS) [Staphylococcus aureus strain 277]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=242879 CGP92_RS09890 WP_001017131.1 1964653..1965696(-) (vraS) [Staphylococcus aureus strain 277]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1