Detailed information NTG0242716

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CGP87_RS13910
• Genome accession: NZ_CP022892
• Coordinates: 2664003..2664890 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 54
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2659003..2669890

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CGP87_RS13875	-	2659022..2659114 (+)	93	WP_010956583.1	hypothetical protein	-
CGP87_RS13880 (CGP87_02497)	-	2659222..2659719 (-)	498	WP_001065268.1	glutathione peroxidase	-
CGP87_RS13885	-	2659729..2659989 (-)	261	WP_001789910.1	hypothetical protein	-
CGP87_RS13895	-	2660371..2660484 (-)	114	WP_011447078.1	hypothetical protein	-
CGP87_RS13900 (CGP87_02498)	-	2661143..2663143 (-)	2001	WP_000776751.1	ABC transporter permease	-
CGP87_RS13905 (CGP87_02499)	-	2663140..2663895 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
CGP87_RS13910 (CGP87_02500)	braS	2664003..2664890 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CGP87_RS13915 (CGP87_02501)	braR	2664901..2665566 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CGP87_RS13920 (CGP87_02502)	-	2665592..2665792 (-)	201	WP_000604728.1	hypothetical protein	-
CGP87_RS13925 (CGP87_02503)	-	2665990..2667414 (+)	1425	WP_000953744.1	alkaline phosphatase	-
CGP87_RS14410	-	2667484..2667594 (+)	111	WP_001791296.1	hypothetical protein	-
CGP87_RS13935 (CGP87_02505)	-	2667697..2668152 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
CGP87_RS13940 (CGP87_02506)	-	2668397..2669158 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=242716 CGP87_RS13910 WP_000143419.1 2664003..2664890(-) (braS) [Staphylococcus aureus strain 54]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=242716 CGP87_RS13910 WP_000143419.1 2664003..2664890(-) (braS) [Staphylococcus aureus strain 54]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997