Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   CJO35_RS06350 Genome accession   NZ_CP022874
Coordinates   1255328..1255966 (+) Length   212 a.a.
NCBI ID   WP_009328831.1    Uniprot ID   D9YRK8
Organism   Bacillus sp. 1s-1     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1250328..1260966
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CJO35_RS06325 (CJO35_06325) - 1250774..1251850 (+) 1077 WP_151025719.1 ABC transporter ATP-binding protein -
  CJO35_RS06330 (CJO35_06330) - 1251852..1252775 (+) 924 WP_011197769.1 ATP-binding cassette domain-containing protein -
  CJO35_RS06335 (CJO35_06335) - 1253006..1253584 (+) 579 WP_003180619.1 GNAT family N-acetyltransferase -
  CJO35_RS06340 (CJO35_06340) spxA 1253762..1254157 (+) 396 WP_009328833.1 transcriptional regulator SpxA -
  CJO35_RS06345 (CJO35_06345) - 1254380..1255042 (-) 663 WP_009328832.1 TerC family protein -
  CJO35_RS21680 - 1255218..1255346 (+) 129 Protein_1179 hypothetical protein -
  CJO35_RS06350 (CJO35_06350) mecA 1255328..1255966 (+) 639 WP_009328831.1 adaptor protein MecA Regulator
  CJO35_RS06355 (CJO35_06355) - 1256125..1257141 (+) 1017 WP_011197770.1 tripartite tricarboxylate transporter substrate binding protein -
  CJO35_RS06360 (CJO35_06360) - 1257244..1257699 (+) 456 WP_009328829.1 tripartite tricarboxylate transporter TctB family protein -
  CJO35_RS06365 (CJO35_06365) - 1257722..1259227 (+) 1506 WP_021837281.1 tripartite tricarboxylate transporter permease -
  CJO35_RS06370 (CJO35_06370) - 1259247..1259963 (-) 717 WP_009328827.1 response regulator -

Sequence

Protein


Download         Length: 212 a.a.        Molecular weight: 25115.14 Da        Isoelectric Point: 4.2198

>NTDB_id=242388 CJO35_RS06350 WP_009328831.1 1255328..1255966(+) (mecA) [Bacillus sp. 1s-1]
MEIERINEHTVKFYISYGDIEDRGFDREEIWYNRERSEELFWEMMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTRAQL
SKDGQKLELPIPEDKKQHVAEESLDALLDDFQKEEQAEEQKLQFVLKFDDFEDLISLSKMSVSGCQTTLYSHENRYYLFV
DFNELPDEEVENQLSILLEYASESKMTIHMLKEYGKLIAADHALHTIKKHFA

Nucleotide


Download         Length: 639 bp        

>NTDB_id=242388 CJO35_RS06350 WP_009328831.1 1255328..1255966(+) (mecA) [Bacillus sp. 1s-1]
ATGGAAATCGAAAGAATAAACGAACACACGGTTAAGTTTTATATTTCCTACGGTGATATCGAAGACCGCGGGTTTGACAG
AGAAGAAATTTGGTACAATCGAGAACGCAGTGAAGAGCTTTTTTGGGAAATGATGGACGAAGTGCACGAAGAAGAAGAGT
TTGCCGTTGAAGGCCCCCTTTGGATTCAAGTGCAGGCCCTTGACAAGGGATTGGAAATCATTGTGACAAGAGCTCAGTTG
TCCAAAGACGGACAAAAGCTGGAACTGCCGATTCCTGAAGATAAAAAACAGCATGTAGCAGAAGAAAGCCTTGATGCTTT
GCTTGACGACTTTCAAAAAGAAGAGCAGGCAGAAGAGCAGAAACTGCAGTTTGTTTTAAAATTTGACGATTTTGAGGATT
TAATCTCACTGTCAAAAATGTCTGTCAGCGGTTGCCAAACGACATTGTACTCTCATGAAAACCGCTATTATTTATTCGTG
GATTTCAATGAACTGCCTGATGAAGAGGTGGAAAACCAGCTGAGCATTCTGCTGGAATATGCTTCAGAATCAAAGATGAC
GATTCATATGCTGAAAGAGTATGGAAAACTGATTGCAGCGGATCATGCTCTTCATACAATAAAAAAGCACTTTGCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D9YRK8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

82.949

100

0.849

Multiple sequence alignment