Detailed information NTG0241964

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CGP86_RS13595
• Genome accession: NZ_CP022720
• Coordinates: 2629896..2630783 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain 135
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2624896..2635783

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CGP86_RS13560	-	2624916..2625008 (+)	93	WP_010956583.1	hypothetical protein	-
CGP86_RS13565 (CGP86_02471)	-	2625116..2625613 (-)	498	WP_001065268.1	glutathione peroxidase	-
CGP86_RS13570	-	2625623..2625883 (-)	261	WP_001791974.1	hypothetical protein	-
CGP86_RS13580	-	2626265..2626378 (-)	114	Protein_2519	hypothetical protein	-
CGP86_RS13585	-	2627037..2629036 (-)	2000	Protein_2520	ABC transporter permease	-
CGP86_RS13590 (CGP86_02474)	-	2629033..2629788 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
CGP86_RS13595 (CGP86_02475)	braS	2629896..2630783 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CGP86_RS13600 (CGP86_02476)	braR	2630794..2631459 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CGP86_RS13605 (CGP86_02477)	-	2631485..2631685 (-)	201	WP_000604727.1	hypothetical protein	-
CGP86_RS13610 (CGP86_02478)	-	2631883..2633307 (+)	1425	WP_000953748.1	alkaline phosphatase	-
CGP86_RS14215	-	2633377..2633487 (+)	111	WP_001791296.1	hypothetical protein	-
CGP86_RS13620 (CGP86_02480)	-	2633590..2634045 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
CGP86_RS13625 (CGP86_02481)	-	2634290..2635051 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=241964 CGP86_RS13595 WP_000143417.1 2629896..2630783(-) (braS) [Staphylococcus aureus strain 135]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=241964 CGP86_RS13595 WP_000143417.1 2629896..2630783(-) (braS) [Staphylococcus aureus strain 135]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99