Detailed information NTG0241959

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CGP86_RS09915
• Genome accession: NZ_CP022720
• Coordinates: 1940684..1941727 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 135
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1935684..1946727

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CGP86_RS09885 (CGP86_01826)	-	1936106..1937362 (-)	1257	WP_072419726.1	aminopeptidase	-
CGP86_RS09890 (CGP86_01827)	-	1937365..1937565 (-)	201	WP_000180460.1	DUF1128 family protein	-
CGP86_RS09895 (CGP86_01828)	-	1937712..1938176 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
CGP86_RS09900 (CGP86_01829)	-	1938183..1938458 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
CGP86_RS09905 (CGP86_01830)	-	1938736..1939953 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
CGP86_RS09910 (CGP86_01831)	vraR	1940065..1940694 (-)	630	WP_000153536.1	two-component system response regulator VraR	Regulator
CGP86_RS09915 (CGP86_01832)	vraS	1940684..1941727 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
CGP86_RS09920 (CGP86_01833)	liaF	1941724..1942425 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
CGP86_RS09925 (CGP86_01834)	-	1942440..1942826 (-)	387	WP_001110179.1	hypothetical protein	-
CGP86_RS09930 (CGP86_01835)	map	1943043..1943801 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
CGP86_RS09940 (CGP86_01836)	-	1944332..1945318 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
CGP86_RS09950 (CGP86_01837)	-	1945808..1946221 (-)	414	WP_001566709.1	hypothetical protein	-
CGP86_RS09955	-	1946250..1946360 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=241959 CGP86_RS09915 WP_001017131.1 1940684..1941727(-) (vraS) [Staphylococcus aureus strain 135]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=241959 CGP86_RS09915 WP_001017131.1 1940684..1941727(-) (vraS) [Staphylococcus aureus strain 135]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGCATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1