Detailed information NTG0241875

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CGP83_RS10015
• Genome accession: NZ_CP022717
• Coordinates: 1971445..1972488 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 27
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1966445..1977488

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CGP83_RS09985 (CGP83_01839)	-	1966866..1968122 (-)	1257	WP_078103411.1	aminopeptidase	-
CGP83_RS09990 (CGP83_01840)	-	1968125..1968325 (-)	201	WP_000180462.1	DUF1128 family protein	-
CGP83_RS09995 (CGP83_01841)	-	1968472..1968936 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
CGP83_RS10000 (CGP83_01842)	-	1968943..1969218 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
CGP83_RS10005 (CGP83_01843)	-	1969496..1970713 (+)	1218	WP_000037088.1	YihY/virulence factor BrkB family protein	-
CGP83_RS10010 (CGP83_01844)	vraR	1970826..1971455 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
CGP83_RS10015 (CGP83_01845)	vraS	1971445..1972488 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
CGP83_RS10020 (CGP83_01846)	liaF	1972485..1973186 (-)	702	WP_000149068.1	cell wall-active antibiotics response protein LiaF	-
CGP83_RS10025 (CGP83_01847)	-	1973201..1973587 (-)	387	WP_001110179.1	hypothetical protein	-
CGP83_RS10030 (CGP83_01848)	map	1973804..1974562 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
CGP83_RS10050 (CGP83_01849)	-	1975259..1976245 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
CGP83_RS10055 (CGP83_01850)	-	1976434..1976847 (-)	414	WP_025174475.1	hypothetical protein	-
CGP83_RS10060	-	1976876..1976986 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=241875 CGP83_RS10015 WP_001017131.1 1971445..1972488(-) (vraS) [Staphylococcus aureus strain 27]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=241875 CGP83_RS10015 WP_001017131.1 1971445..1972488(-) (vraS) [Staphylococcus aureus strain 27]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATTTTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATT
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCGGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1