Detailed information NTG0241630

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: C5Y81_RS13355
• Genome accession: NZ_CP028470
• Coordinates: 2583079..2585160 (+)
• Length: 693 a.a.
• NCBI ID: WP_110164489.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain IT4-R
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2578079..2590160

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C5Y81_RS13330 (C5Y81_13330)	-	2578150..2578368 (+)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-
C5Y81_RS13335 (C5Y81_13335)	-	2578757..2579188 (+)	432	WP_000455858.1	CHAP domain-containing protein	-
C5Y81_RS13340 (C5Y81_13340)	-	2579327..2580604 (-)	1278	WP_001180327.1	hydroxymethylglutaryl-CoA reductase, degradative	-
C5Y81_RS13345 (C5Y81_13345)	-	2580858..2582024 (+)	1167	WP_000151986.1	hydroxymethylglutaryl-CoA synthase	-
C5Y81_RS13350 (C5Y81_13350)	-	2582195..2582716 (-)	522	WP_000262592.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
C5Y81_RS13355 (C5Y81_13355)	clpE	2583079..2585160 (+)	2082	WP_110164489.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
C5Y81_RS13360 (C5Y81_13360)	-	2585227..2585397 (-)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
C5Y81_RS13365 (C5Y81_13365)	feoB	2585410..2587404 (-)	1995	WP_052997670.1	ferrous iron transport protein B	-
C5Y81_RS13370 (C5Y81_13370)	-	2587416..2587643 (-)	228	WP_000932073.1	ferrous iron transport protein A	-

Sequence

Protein

• Length: 693 a.a.
• Molecular weight: 77089.39 Da
• Isoelectric Point: 4.6161

>NTDB_id=241630 C5Y81_RS13355 WP_110164489.1 2583079..2585160(+) (clpE) [Staphylococcus aureus strain IT4-R]
MNNNFFNSDFDSILRRMMQDMQSSNQTSNKKYYINGKEVSPEELAQFTQQGGNHSAEQSAQAFQQGGNGNYLEQIGRNLT
QEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISIDISSLEAGT
QYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDEYRNNILKDA
ALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITAAHLSAQSPA
IDKVATEKRISELEHDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPVSQMDDNDIE
RLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDALIRLDMSEY
SDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVINFKNTIIIC
TSNAGFGNGTDQEYDDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMNVSQDAKDWLI
EEGYDEDLGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2082 bp

>NTDB_id=241630 C5Y81_RS13355 WP_110164489.1 2583079..2585160(+) (clpE) [Staphylococcus aureus strain IT4-R]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAGCTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTAGCACAATTTACGCAACAGGGTGGTAATC
ATTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGGTGGCAATGGCAATTATTTAGAACAAATTGGTCGCAATCTTACG
CAAGAGGCTCGTGACGGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAATCCAAGAGACTGCAGAAGTCTTAAGTAG
ACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGGGTTGGTAAAACTGCGATTGTCGAAGGTTTAGCGCAAGCAA
TCGTTGAAGGGAACGTACCTGCAGCAATCAAAGATAAAGAAATTATATCTATAGATATTTCATCGCTTGAAGCTGGAACG
CAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAAATCATCACAAAATGCTGTGCTCTTCTT
TGACGAAATTCACCAAATCATCGGTTCCGGTGCAACTGGAAGTGATTCCGGTAGTAAAGGGTTATCTGATATTTTAAAAC
CAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACGACTCAAGATGAATATCGAAACAATATTCTTAAAGATGCT
GCATTAACGCGCAGATTTAATGAAGTACTTGTTAATGAACCAAGTGCTAAAGATACTGTTGAAATTTTAAAAGGTATTCG
CGAAAAATTCGAAGAACACCATCAAGTAAAATTACCAGATGACGTATTAAAAGCATGTGTTGACTTATCAATTCAATATA
TTCCACAACGATTATTACCAGATAAAGCAATCGATGTGTTAGATATTACAGCAGCACATTTATCTGCACAAAGCCCTGCT
ATTGATAAAGTCGCGACTGAAAAACGTATTTCTGAATTGGAACATGATAAGCGTAAAGCGGTAAGTGCTGAAGAATATAA
AAAAGCTGACGACATTCAAAATGAAATCAAATCATTACAAGATAAATTAGAAAATAGTAATGGTGAACATACTGCCGTTG
CTACTGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTTTCTCAAATGGATGATAACGATATTGAA
CGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGGTCAAGATCAAGCTGTAGAAATGGTTTCTCGTGCAAT
TCGCCGTAATCGTGCTGGGTTTGATGACGGCAACCGTCCAATTGGCAGTTTCCTATTTGTTGGCCCTACTGGTGTTGGTA
AAACAGAGCTTGCTAAACAATTAGCAATTGATCTATTTGGTAATAAAGATGCACTGATTCGACTTGATATGAGTGAATAT
AGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGGTTATGTCGGTTATGATGACAATTCAAATACGTTAAC
TGAAAAAGTACGCCGTAATCCATATTCAGTCATTCTATTTGATGAAATCGAAAAAGCAAATCCACAAATTTTAACATTGT
TATTACAAGTAATGGATGATGGTAATTTGACTGATGGTCAAGGTAATGTCATCAACTTTAAAAATACAATTATTATTTGT
ACATCAAATGCTGGCTTTGGTAACGGTACAGACCAAGAATACGATGACATTATGCATGAAATGAAAAAATTCTTCCGCCC
TGAATTCCTTAACCGCTTCAACGGTATCGTTGAATTCTTACATTTAGATAAAGATGCATTACAAGATATCGTCAACTTAT
TATTAGACGATGTCCAAGTAACATTAGATAAAAAAGGTATTACGATGAATGTCTCTCAAGATGCAAAAGATTGGTTAATT
GAAGAAGGTTATGATGAAGACTTAGGCGCACGCCCATTAAGACGTATTGTTGAACAGCAAGTACGTGACAAAATTACAGA
TTACTATTTAGATCATACTGACGTTAAACATGTGGATTTAGATATCGAGGACAATGAATTAGTCGTCAAAGGTAAATCAT
GA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (439-594)

• ATPase family associated with various cellular activities (AAA) (AAA) (114-248)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (602-673)

• AAA lid domain (AAA_lid_9) (255-354)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.131	92.641	0.446
clpC	Lactococcus lactis subsp. cremoris KW2	45.51	94.805	0.431
clpE	Streptococcus pneumoniae Rx1	47.302	90.909	0.43
clpE	Streptococcus pneumoniae TIGR4	47.302	90.909	0.43
clpE	Streptococcus pneumoniae R6	47.302	90.909	0.43
clpE	Streptococcus pneumoniae D39	47.302	90.909	0.43
clpC	Bacillus subtilis subsp. subtilis str. 168	43.323	97.258	0.421
clpC	Streptococcus thermophilus LMD-9	44.918	88.023	0.395
clpC	Streptococcus thermophilus LMG 18311	44.754	88.023	0.394
clpC	Streptococcus pneumoniae TIGR4	43.942	89.322	0.392
clpC	Streptococcus pneumoniae Rx1	43.942	89.322	0.392
clpC	Streptococcus pneumoniae D39	43.942	89.322	0.392
clpC	Streptococcus mutans UA159	43.577	88.745	0.387
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.562	92.352	0.384