Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   CGP84_RS10850 Genome accession   NZ_CP022682
Coordinates   2102435..2103151 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 78     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2097435..2108151
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGP84_RS10820 (CGP84_01987) - 2097780..2098406 (+) 627 WP_000522380.1 nitroreductase family protein -
  CGP84_RS10825 (CGP84_01988) - 2098640..2099425 (+) 786 WP_000867953.1 carbon-nitrogen family hydrolase -
  CGP84_RS10830 hld 2100023..2100103 (-) 81 WP_000046023.1 delta-hemolysin -
  CGP84_RS10835 (CGP84_01989) - 2100394..2100957 (+) 564 WP_001105716.1 accessory gene regulator AgrB -
  CGP84_RS10840 (CGP84_01990) - 2100959..2101099 (+) 141 WP_001094303.1 cyclic lactone autoinducer peptide -
  CGP84_RS10845 (CGP84_01991) - 2101124..2102416 (+) 1293 WP_001807128.1 GHKL domain-containing protein -
  CGP84_RS10850 (CGP84_01992) agrA 2102435..2103151 (+) 717 WP_000688492.1 LytTR family DNA-binding domain-containing protein Regulator
  CGP84_RS10855 - 2103223..2103330 (+) 108 WP_031927410.1 hypothetical protein -
  CGP84_RS10860 (CGP84_01993) - 2103518..2104477 (-) 960 WP_047213656.1 carbohydrate kinase -
  CGP84_RS10865 (CGP84_01994) - 2104474..2105958 (-) 1485 WP_000141423.1 sucrose-6-phosphate hydrolase -
  CGP84_RS10870 (CGP84_01995) - 2106107..2107057 (-) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=241629 CGP84_RS10850 WP_000688492.1 2102435..2103151(+) (agrA) [Staphylococcus aureus strain 78]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=241629 CGP84_RS10850 WP_000688492.1 2102435..2103151(+) (agrA) [Staphylococcus aureus strain 78]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACTTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCAAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCAGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment