Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   CHN56_RS05165 Genome accession   NZ_CP022654
Coordinates   1094439..1095095 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain SCDB 291     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1089439..1100095
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CHN56_RS05145 (CHN56_01028) spxH 1089678..1090580 (+) 903 WP_024085126.1 protease adaptor protein SpxH -
  CHN56_RS21540 (CHN56_01029) - 1090866..1091033 (+) 168 WP_003155026.1 hypothetical protein -
  CHN56_RS05155 (CHN56_01030) pepF 1091071..1092900 (-) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  CHN56_RS05160 (CHN56_01031) - 1093128..1094288 (-) 1161 WP_094247076.1 competence protein CoiA family protein -
  CHN56_RS05165 (CHN56_01032) mecA 1094439..1095095 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  CHN56_RS21740 - 1095078..1095188 (-) 111 Protein_1021 adaptor protein MecA -
  CHN56_RS05170 (CHN56_01033) - 1095371..1096027 (+) 657 WP_003155033.1 TerC family protein -
  CHN56_RS05175 (CHN56_01034) spx 1096085..1096480 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  CHN56_RS05180 (CHN56_01035) - 1096659..1097237 (-) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  CHN56_RS05185 (CHN56_01036) - 1097355..1098542 (-) 1188 WP_094247077.1 putative glycoside hydrolase -
  CHN56_RS05190 (CHN56_01037) oppF 1098649..1099566 (-) 918 WP_070081625.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=241290 CHN56_RS05165 WP_003155032.1 1094439..1095095(-) (mecA) [Bacillus velezensis strain SCDB 291]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=241290 CHN56_RS05165 WP_003155032.1 1094439..1095095(-) (mecA) [Bacillus velezensis strain SCDB 291]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCTTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment