Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   SM12261_RS08710 Genome accession   NZ_CP028414
Coordinates   1721835..1724666 (-) Length   943 a.a.
NCBI ID   WP_001152871.1    Uniprot ID   -
Organism   Streptococcus mitis NCTC 12261     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1716835..1729666
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM12261_RS08690 (SM12261_1675) spx 1717185..1717583 (-) 399 WP_000591165.1 transcriptional regulator Spx -
  SM12261_RS08700 (SM12261_1676) mgtA 1717718..1720378 (-) 2661 WP_000858860.1 magnesium-translocating P-type ATPase -
  SM12261_RS08705 (SM12261_1677) - 1720781..1721842 (-) 1062 WP_001042845.1 M24 family metallopeptidase -
  SM12261_RS08710 (SM12261_1678) uvrA 1721835..1724666 (-) 2832 WP_001152871.1 excinuclease ABC subunit UvrA Machinery gene
  SM12261_RS08715 (SM12261_1679) - 1724798..1725742 (+) 945 WP_000815623.1 magnesium transporter CorA family protein -
  SM12261_RS08720 (SM12261_1680) - 1725754..1726431 (+) 678 WP_000078009.1 DUF1129 domain-containing protein -
  SM12261_RS08725 (SM12261_1681) - 1726572..1727606 (+) 1035 WP_000626031.1 S66 family peptidase -
  SM12261_RS08730 (SM12261_1682) - 1727712..1727975 (+) 264 WP_000166114.1 SemiSWEET family transporter -
  SM12261_RS08735 (SM12261_1683) - 1728059..1728622 (-) 564 WP_000166574.1 DNA-3-methyladenine glycosylase I -
  SM12261_RS08740 (SM12261_1684) ruvA 1728632..1729225 (-) 594 WP_000273422.1 Holliday junction branch migration protein RuvA Machinery gene

Sequence

Protein


Download         Length: 943 a.a.        Molecular weight: 104063.05 Da        Isoelectric Point: 6.2906

>NTDB_id=241166 SM12261_RS08710 WP_001152871.1 1721835..1724666(-) (uvrA) [Streptococcus mitis NCTC 12261]
MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGL
SPAISIDQKTTSKNPRSTVGTTTEINDYLRLLYARVGTPYCINGHGAIKASSVEQIVDKVLELPERQRLQILAPVIRKKK
GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRLFDSIEAALRIAEGYVIIDTMDD
SELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCSECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNML
EQAMTAFGVDMDKPFEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVVNNIKRRYHETNSDYTRTQMRLYM
NELTCGTCHGYRLNDQALSVRVGGAQGPHIGEISDLSIADHLELVSQLTLSENEAIIARPILKEIKDRLTFLNNVGLNYL
TLSRSAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLI
DVGPGAGVFGGEIVAAGTPKQVARNSKSITGQYLSGKRAIPVPEERRVGNGRFIEVTGARENNLQNVTARFPLGKFIAVT
GVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHVDRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVEFF
QHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYILDEPTTGLHTEDIARLLKVLARFVD
DGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGTIIATGTPEEVAANEASYTGQYLKGKLHHE

Nucleotide


Download         Length: 2832 bp        

>NTDB_id=241166 SM12261_RS08710 WP_001152871.1 1721835..1724666(-) (uvrA) [Streptococcus mitis NCTC 12261]
ATGCAAGATAAAATTGTCATTCATGGGGCGCGTGCCCATAATTTAAAAAATATTGATGTGGAGATTCCGCGAGACAAGTT
GGTTGTTGTGACCGGTTTGTCAGGTTCAGGGAAATCCAGTCTGGCCTTTGATACCCTCTATGCGGAGGGGCAACGTCGCT
ATGTGGAGAGTTTGTCAGCCTATGCTCGTCAGTTCTTGGGGAATATGGAGAAGCCTGATGTAGATGCTATTGATGGTCTC
AGCCCAGCTATTTCTATCGACCAGAAAACGACTAGTAAAAACCCTCGCTCGACGGTGGGAACAACGACTGAAATCAATGA
CTATCTGCGTCTCCTCTACGCACGTGTGGGGACGCCTTACTGTATCAACGGGCATGGAGCTATCAAGGCCTCTTCAGTGG
AGCAAATCGTGGATAAGGTTTTAGAATTGCCTGAACGCCAGCGCTTGCAGATCTTGGCCCCTGTCATCCGCAAGAAAAAA
GGCCAACATAAGAGTGTTATCGAGAAGGTTCAGAAAGATGGGTATGTCCGTGTCCGTGTGGATGGGGAAGTCTATGATGT
GACCGAAGTGCCAGAGTTATCTAAGAGCAAGCAACACAATATTGATGTCGTGGTTGATCGTATTGTTATCAAGGAGGGCA
TTCGTAGTCGTCTCTTTGATTCTATTGAGGCTGCCCTTCGTATCGCAGAAGGCTATGTCATTATCGACACTATGGACGAC
TCTGAGTTGCTCTTCTCTGAGCATTATGCCTGTCCAGTTTGTGGCTTTACTGTTCCAGAGTTAGAGCCGCGTCTCTTCTC
CTTCAATGCTCCTTTTGGTTCTTGTAGTGAGTGTGATGGCTTGGGCATCAAGCTGGAGGTGGATACTGATTTGGTAGTGC
CAGATGCCAGCAAAACCTTACGTGAGGGAGCCTTGGCTCCGTGGAATCCTATCTCATCCAACTACTATCCAAACATGCTA
GAGCAGGCTATGACAGCCTTTGGAGTGGATATGGATAAGCCTTTTGAGGACTTGTCAGAAGAAGATAAGAACTTGATTCT
CTACGGCTCAGATGGTAAGGAATTCCATTTCCACTATGAGAATGAATTTGGTGGCGTGCGCGATATCGATATTCCTTTTG
AGGGAGTTGTTAATAATATCAAACGTCGCTACCATGAAACTAATAGTGACTACACTCGCACCCAGATGCGCCTTTACATG
AATGAGCTGACCTGCGGAACCTGTCATGGTTACCGTCTCAATGACCAGGCCTTGTCTGTCCGTGTTGGTGGTGCGCAAGG
ACCACATATCGGAGAAATTTCAGACCTGTCTATCGCAGACCACTTGGAATTAGTCAGTCAGTTGACTCTTTCTGAAAATG
AAGCCATCATTGCTCGGCCCATTCTCAAGGAAATCAAGGACCGTTTGACTTTCCTTAATAACGTGGGTCTTAACTATCTG
ACTCTGTCTCGTTCAGCAGGAACTCTTTCAGGTGGGGAAAGTCAGCGTATTCGCTTGGCGACCCAGATTGGTTCTAACCT
ATCAGGTGTTCTTTATATTCTAGACGAGCCGTCAATCGGTCTTCACCAGAGGGATAATGACCGTCTGATTGCCAGTCTCA
AAAAGATGCGTGACTTGGGCAATACTCTTATCGTGGTGGAACATGACGAAGATACCATGCGTGAGGCTGATTATCTGATT
GACGTTGGTCCTGGTGCGGGTGTTTTTGGTGGGGAGATTGTTGCGGCAGGTACGCCCAAACAGGTAGCTCGTAACAGTAA
GTCTATCACAGGCCAGTACTTGTCAGGCAAACGTGCCATTCCAGTACCAGAAGAACGCCGTGTTGGTAATGGTCGTTTTA
TCGAGGTGACGGGAGCGCGTGAGAACAACCTGCAAAATGTCACAGCTCGCTTCCCACTAGGAAAATTCATCGCAGTGACA
GGGGTGTCGGGCTCAGGGAAATCGACCCTAATCAATAGCATTCTCAAAAAAGCTATTGCCCAGAAGCTCAACCGCAATTC
AGACAAACCTGGTAAGTTTAAAACGATTACAGGGATTGAGCATGTAGACCGCTTGATTGATATTGATCAGAGCCCTATCG
GACGAACGCCGAGGTCTAACCCTGCTACCTATACGGGAGTTTTTGACGATATACGTGACCTCTTTGCCCAGACAAATGAG
GCTAAGATTCGTGGTTACAAAAAGGGACGTTTCAGTTTCAATGTCAAGGGTGGTCGTTGTGAAGCCTGCTCAGGTGACGG
GATTATCAAGATTGAGATGCACTTCTTGCCAGATGTTTACGTGGCTTGTGAAGTCTGCCACGGGACTCGCTACAATAGTG
AAACCCTAGAAGTTCATTACAAGGAAAAGAATATCTCGCAGGTCTTGGACATGACTGTCAATGATGCGGTGGAATTTTTC
CAACACATTCCGAAAATTCAACGCAAACTTCAGACTATCAAGGATGTAGGGCTAGGCTATGTGACGCTAGGTCAACCAGC
TACCACTCTTTCTGGGGGAGAAGCCCAGCGTATGAAGCTGGCTAGCGAACTCCACAAACGCTCGACAGGCAAGTCATTCT
ATATTCTGGATGAACCGACGACAGGACTCCATACAGAGGATATCGCTCGCTTGCTCAAGGTTTTAGCTCGCTTTGTTGAC
GATGGCAATACAGTCCTTGTTATCGAGCACAATTTAGACGTTATCAAGACAGCAGACCATATTATTGACTTGGGACCTGA
GGGCGGTGTCGGTGGTGGAACCATCATCGCAACAGGAACTCCAGAAGAAGTAGCGGCCAATGAAGCCAGCTACACAGGAC
AGTATTTGAAAGGAAAGTTACATCATGAATAA

Domains

Predicted by InterProScan.

UvrA DNA-binding domain (UvrA_DNA-bind)

(288-396)

ABC transporter (ABC_tran)

(624-860)

UvrA interaction domain (UvrA_inter)

(132-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

98.727

100

0.987
  uvrA Streptococcus pneumoniae TIGR4

98.727

100

0.987
  uvrA Streptococcus pneumoniae D39

98.727

100

0.987

Multiple sequence alignment