Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR/comR1   Type   Regulator
Locus tag   SM12261_RS06440 Genome accession   NZ_CP028414
Coordinates   1236169..1236351 (-) Length   60 a.a.
NCBI ID   WP_002877065.1    Uniprot ID   -
Organism   Streptococcus mitis NCTC 12261     
Function   repress natural transformation (predicted from homology)   
Competence regulation

Genomic Context

Location: 1231169..1241351
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM12261_RS06415 (SM12261_1248) - 1231203..1231763 (-) 561 WP_000915275.1 ECF transporter S component -
  SM12261_RS06420 (SM12261_1249) thiE 1232104..1232733 (-) 630 WP_000468570.1 thiamine phosphate synthase -
  SM12261_RS06425 (SM12261_1250) thiM 1232723..1233517 (-) 795 WP_000202461.1 hydroxyethylthiazole kinase -
  SM12261_RS06430 (SM12261_1251) - 1233752..1234420 (-) 669 WP_000449832.1 TenA family protein -
  SM12261_RS06435 (SM12261_1252) lctO 1234873..1236009 (-) 1137 WP_000120723.1 L-lactate oxidase -
  SM12261_RS06440 comR/comR1 1236169..1236351 (-) 183 WP_002877065.1 hypothetical protein Regulator
  SM12261_RS09430 comR/comR1 1236494..1236778 (-) 285 WP_158077646.1 hypothetical protein Regulator
  SM12261_RS06450 (SM12261_1256) - 1237110..1237670 (-) 561 WP_000111604.1 TetR/AcrR family transcriptional regulator -
  SM12261_RS06455 (SM12261_1257) - 1237924..1238547 (+) 624 WP_000483067.1 cysteine hydrolase -
  SM12261_RS06460 (SM12261_1258) pyrE 1238598..1239230 (-) 633 WP_000170898.1 orotate phosphoribosyltransferase -
  SM12261_RS06465 (SM12261_1259) pyrF 1239264..1239965 (-) 702 WP_001206736.1 orotidine-5'-phosphate decarboxylase -

Sequence

Protein


Download         Length: 60 a.a.        Molecular weight: 6987.01 Da        Isoelectric Point: 4.6653

>NTDB_id=241145 SM12261_RS06440 WP_002877065.1 1236169..1236351(-) (comR/comR1) [Streptococcus mitis NCTC 12261]
MNEILSVTTLQVYKPGISVFEAKCYLYFENDKNKAKELYHSATILAEQFDDKVLENEKII

Nucleotide


Download         Length: 183 bp        

>NTDB_id=241145 SM12261_RS06440 WP_002877065.1 1236169..1236351(-) (comR/comR1) [Streptococcus mitis NCTC 12261]
ATGAATGAAATTTTATCAGTAACAACGTTGCAAGTCTATAAACCTGGAATTTCAGTATTTGAAGCTAAGTGCTATCTTTA
TTTTGAAAATGATAAAAATAAAGCAAAGGAACTTTATCACTCAGCAACTATACTAGCTGAACAATTTGATGATAAAGTAT
TAGAAAATGAAAAGATTATTTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(1-56)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

40.741

90

0.367

Multiple sequence alignment