Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   SM12261_RS04780 Genome accession   NZ_CP028414
Coordinates   907592..908056 (+) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus mitis NCTC 12261     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 902592..913056
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SM12261_RS04745 (SM12261_0923) dhaL 903396..903971 (+) 576 WP_001100267.1 dihydroxyacetone kinase subunit DhaL -
  SM12261_RS04750 (SM12261_0924) dhaM 903971..904345 (+) 375 WP_000534739.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  SM12261_RS04760 (SM12261_0925) - 904941..905942 (+) 1002 WP_000344676.1 hypothetical protein -
  SM12261_RS04765 - 905939..906136 (+) 198 WP_000658758.1 hypothetical protein -
  SM12261_RS04770 (SM12261_0926) - 906175..906867 (+) 693 WP_000120611.1 YjjG family noncanonical pyrimidine nucleotidase -
  SM12261_RS04775 (SM12261_0927) - 906929..907582 (+) 654 WP_000401338.1 uracil-DNA glycosylase -
  SM12261_RS04780 (SM12261_0928) mutX 907592..908056 (+) 465 WP_001135768.1 NUDIX hydrolase Machinery gene
  SM12261_RS04785 (SM12261_0929) - 908069..909337 (+) 1269 WP_000924473.1 dihydroorotase -
  SM12261_RS04790 (SM12261_0930) - 909379..910740 (+) 1362 WP_000283632.1 MATE family efflux transporter -
  SM12261_RS04795 (SM12261_0931) - 910894..911862 (+) 969 WP_000025262.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  SM12261_RS04800 (SM12261_0932) - 911878..912870 (+) 993 WP_000448715.1 alpha-ketoacid dehydrogenase subunit beta -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=241128 SM12261_RS04780 WP_001135768.1 907592..908056(+) (mutX) [Streptococcus mitis NCTC 12261]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=241128 SM12261_RS04780 WP_001135768.1 907592..908056(+) (mutX) [Streptococcus mitis NCTC 12261]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAACGGGAAAGAACTGCTTATGCTCCACCGTAATAAGAAGCCAAATGA
TGTTCATGAAGGAAAATGGATTGGTGTGGGTGGTAAGCTAGAGCGAGGAGAGACACCTCAGGAATGCGCGGCGCGTGAAA
TCCTTGAGGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTCGAGGGGGATTTGATTGACTGCAATGAGGGGACGCTGGAATGGGTTCC
TTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCATACCTTTGTTGAGTGGCTTTTAGAGGACAAACCCTTCT
TTTCAGCTAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTTTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987