Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   Sp14A_RS08185 Genome accession   NZ_CP022601
Coordinates   1602799..1605057 (+) Length   752 a.a.
NCBI ID   WP_115130639.1    Uniprot ID   A0A345VLJ9
Organism   Streptococcus pluranimalium strain 14A0014     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1597799..1610057
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Sp14A_RS08155 (Sp14A_16870) - 1598302..1598952 (-) 651 WP_115130635.1 hemolysin III family protein -
  Sp14A_RS08160 (Sp14A_16880) - 1598936..1599415 (-) 480 WP_115130636.1 DUF1836 domain-containing protein -
  Sp14A_RS08165 (Sp14A_16890) - 1599491..1600342 (-) 852 WP_115130637.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  Sp14A_RS08170 (Sp14A_16900) - 1600579..1601313 (-) 735 WP_115130638.1 amino acid ABC transporter ATP-binding protein -
  Sp14A_RS08175 (Sp14A_16910) - 1601313..1601999 (-) 687 WP_104968299.1 amino acid ABC transporter permease -
  Sp14A_RS08180 (Sp14A_16920) - 1602278..1602508 (-) 231 WP_104968300.1 YkuJ family protein -
  Sp14A_RS08185 (Sp14A_16930) clpE 1602799..1605057 (+) 2259 WP_115130639.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  Sp14A_RS08190 (Sp14A_16950) - 1605139..1606484 (+) 1346 WP_205407074.1 IS3 family transposase -
  Sp14A_RS08195 (Sp14A_16960) - 1606542..1607048 (-) 507 WP_115130640.1 ECF transporter S component -
  Sp14A_RS08200 (Sp14A_16970) - 1607186..1607635 (+) 450 WP_115130641.1 NUDIX hydrolase -
  Sp14A_RS08205 (Sp14A_16980) - 1607695..1607997 (+) 303 WP_104968304.1 DUF1827 family protein -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 83659.70 Da        Isoelectric Point: 4.8030

>NTDB_id=241067 Sp14A_RS08185 WP_115130639.1 1602799..1605057(+) (clpE) [Streptococcus pluranimalium strain 14A0014]
MLCQNCQLNESTIHLYTNVNGKQKQVDLCQNCYQIMKTDPKNNLLSNLGRENASSSMNPFFDDFFGDLNNFRAFSGDLPN
SPKTQSGGQGGNNGTGNRHPNAPLGTAQQKPQGLLEEFGINITDIARQGDIDPVIGRDEEILRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDADVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRQDVILFIDEIHEIVGAG
NAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSP
DAIEAAAILSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPQEIDQRLVEAENLKAQATRDEDYERAAYFRDQIAKYK
EMQAQKIDDHDTPVITEQNIEAIIEQKTNIPVGDLKEKEQSQLIHLADDLKSHVIGQDDAVDKIAKAIRRNRVGLGSPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILL
DEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAREGRTNSVLNQLGDFFSPEFMN
RFDGIIEFKALEKENLLTIVDLMLKDVNDRLATNGLHLDVTEKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLE
NPSEKNLRAIMTSNGNIIIKSNTKAEAVVEEN

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=241067 Sp14A_RS08185 WP_115130639.1 1602799..1605057(+) (clpE) [Streptococcus pluranimalium strain 14A0014]
ATGCTTTGTCAAAATTGTCAATTAAACGAATCAACTATTCATTTATATACTAATGTTAATGGCAAACAAAAACAAGTCGA
TCTTTGCCAAAACTGTTATCAAATCATGAAAACAGATCCCAAAAACAACCTTTTATCTAACCTGGGTCGAGAAAACGCAT
CATCTTCTATGAATCCATTTTTTGATGATTTCTTTGGTGACTTAAATAACTTCCGTGCCTTCAGCGGTGACCTTCCAAAC
AGTCCTAAAACACAATCTGGTGGTCAGGGAGGAAACAACGGAACCGGAAATCGTCATCCAAATGCCCCTCTAGGCACTGC
TCAACAGAAGCCTCAAGGACTCTTAGAAGAGTTCGGTATTAATATCACTGATATTGCACGCCAAGGCGATATTGATCCCG
TTATTGGTCGCGATGAAGAAATCCTTCGTGTTATCGAAATTCTAAACCGTCGTACCAAAAATAATCCTGTCCTCATTGGT
GAGCCAGGTGTTGGTAAAACTGCTGTCGTTGAAGGACTGGCTCAAAAGATTGTTGATGCTGATGTTCCTCAAAAACTCCA
AGGAAAACAAGTCATCCGTTTGGATGTTGTCAGTCTTGTTCAAGGAACTGGCATTCGTGGGCAATTTGAAGAACGTATGC
AAAAACTCATGGAAGAAATCCGTAATCGTCAAGATGTGATTCTCTTCATTGATGAGATTCATGAGATTGTTGGTGCAGGC
AATGCTGGTGATGGAAACATGGACGCCGGTAATATCCTAAAACCTGCTCTAGCTCGCGGTGAGCTACAACTAGTCGGTGC
TACTACTCTCAATGAATATCGTATCATTGAAAAAGATGCTGCTCTGGAACGTCGTATGCAGCCCGTCAAAGTTGATGAGC
CAAGTGTTGAGGAAACTATCACCATCTTAAAAGGTATTCAACCAAAATACGAAGACTATCACCATGTCAAATATAGCCCT
GATGCGATTGAAGCAGCAGCTATCCTCTCCAACCGTTACATTCAAGACCGCTTCCTTCCAGATAAGGCTATCGATCTACT
AGATGAAGCTGGATCTAAAATGAATTTAACCTTAAATTTTGTTGATCCACAAGAAATCGATCAACGTCTGGTGGAAGCCG
AAAACCTCAAAGCTCAAGCGACTCGAGATGAAGATTATGAACGCGCAGCTTATTTCCGTGACCAAATTGCTAAATACAAA
GAAATGCAAGCGCAAAAAATCGATGACCACGACACTCCAGTCATCACTGAACAAAATATCGAAGCCATCATTGAACAAAA
AACTAATATTCCAGTCGGCGATCTCAAAGAAAAAGAACAAAGTCAATTAATTCATTTGGCTGACGACCTTAAATCACACG
TTATTGGACAAGACGATGCTGTTGATAAAATCGCAAAAGCCATTCGTCGTAACCGTGTCGGACTTGGTTCGCCAAATCGC
CCAATCGGCTCCTTCCTCTTTGTTGGTCCAACTGGTGTCGGTAAAACTGAACTCTCAAAACAACTAGCAATCGAGCTCTT
TGGTTCAGCAGACAGCATGATTCGCTTTGATATGTCCGAGTACATGGAAAAACATGCCGTCGCCAAACTTGTCGGGGCTC
CTCCAGGTTATGTTGGTTATGAAGAAGCTGGTCAATTAACAGAAAAAGTTCGTCGCAATCCATACTCACTCATTCTCTTG
GATGAAGTTGAGAAAGCTCACCCAGATGTTATGCATATGTTCTTACAAGTTCTTGACGATGGTCGTTTGACTGATGGTCA
AGGTCGTACCGTTAGCTTCAAAGATACCATTATCATCATGACTTCTAATGCTGGAACAGGCAAGGTTGAAGCTTCTGTTG
GATTTGGAGCAGCTCGTGAAGGTCGTACTAACTCCGTTCTTAACCAACTTGGAGACTTCTTTAGCCCAGAATTCATGAAC
CGTTTTGACGGTATTATCGAATTCAAAGCCCTTGAAAAAGAAAATCTCCTTACTATTGTTGATCTCATGCTCAAAGATGT
CAATGATAGACTTGCTACCAACGGTCTTCACCTTGATGTCACCGAGAAAGTTAAGGAAAAATTGGTTGATCTTGGCTATG
ATCCAAAAATGGGAGCTCGTCCACTTCGCAGAACAATTCAAGACCATATCGAAGATGCTATCACAGATTTCTATCTTGAA
AATCCTTCAGAGAAAAATCTCCGTGCCATCATGACTTCTAATGGAAACATCATTATCAAATCAAATACGAAAGCTGAAGC
TGTCGTAGAAGAAAACTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(651-726)

AAA domain (Cdc48 subfamily) (AAA_2)

(480-643)

AAA lid domain (AAA_lid_9)

(295-392)

ATPase family associated with various cellular activities (AAA) (AAA)

(157-276)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

86.418

99.867

0.863
  clpE Streptococcus pneumoniae Rx1

82.649

100

0.83
  clpE Streptococcus pneumoniae D39

82.649

100

0.83
  clpE Streptococcus pneumoniae R6

82.649

100

0.83
  clpE Streptococcus pneumoniae TIGR4

82.649

100

0.83
  clpC Lactococcus lactis subsp. cremoris KW2

75.6

99.734

0.754
  clpC Bacillus subtilis subsp. subtilis str. 168

50.297

89.628

0.451
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.625

84.707

0.395
  clpC Streptococcus pneumoniae Rx1

47.581

82.447

0.392
  clpC Streptococcus pneumoniae D39

47.581

82.447

0.392
  clpC Streptococcus pneumoniae TIGR4

47.419

82.447

0.391
  clpC Streptococcus mutans UA159

47.182

82.58

0.39
  clpC Streptococcus thermophilus LMD-9

46.057

84.309

0.388
  clpC Streptococcus thermophilus LMG 18311

45.741

84.309

0.386

Multiple sequence alignment