Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   FORC62_RS11475 Genome accession   NZ_CP022582
Coordinates   2184933..2185715 (+) Length   260 a.a.
NCBI ID   WP_084943916.1    Uniprot ID   -
Organism   Staphylococcus aureus strain FORC_062     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2179933..2190715
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FORC62_RS11440 (FORC62_2056) - 2180151..2180777 (+) 627 WP_000522381.1 nitroreductase family protein -
  FORC62_RS11450 (FORC62_2057) - 2181138..2181922 (+) 785 Protein_2133 carbon-nitrogen family hydrolase -
  FORC62_RS15445 (FORC62_2057a) - 2182522..2182656 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  FORC62_RS11460 (FORC62_2058) - 2182892..2183455 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  FORC62_RS11465 agrD 2183458..2183601 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  FORC62_RS11470 (FORC62_2059) agrC 2183631..2184914 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  FORC62_RS11475 (FORC62_2060) agrA 2184933..2185715 (+) 783 WP_084943916.1 quorum-sensing response regulator AgrA Regulator
  FORC62_RS11480 - 2185723..2185832 (+) 110 Protein_2139 hypothetical protein -
  FORC62_RS11485 (FORC62_2061) - 2186020..2186979 (-) 960 WP_001253312.1 carbohydrate kinase -
  FORC62_RS11490 (FORC62_2062) - 2186976..2188460 (-) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  FORC62_RS11495 (FORC62_2063) - 2188609..2189559 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 30426.85 Da        Isoelectric Point: 6.8881

>NTDB_id=241004 FORC62_RS11475 WP_084943916.1 2184933..2185715(+) (agrA) [Staphylococcus aureus strain FORC_062]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKNNN
KIIKSVNGVFNCKSCWILTR

Nucleotide


Download         Length: 783 bp        

>NTDB_id=241004 FORC62_RS11475 WP_084943916.1 2184933..2185715(+) (agrA) [Staphylococcus aureus strain FORC_062]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCACATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAAATAATAAT
AAGATAATAAAGTCAGTTAACGGCGTATTCAATTGTAAATCTTGTTGGATTTTAACAAGATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

91.154

0.912

Multiple sequence alignment