Detailed information NTG0241003

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: FORC62_RS10975
• Genome accession: NZ_CP022582
• Coordinates: 2095068..2096111 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain FORC_062
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2090068..2101111

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FORC62_RS10945 (FORC62_1967)	-	2090489..2091745 (-)	1257	WP_001795108.1	aminopeptidase	-
FORC62_RS10950 (FORC62_1968)	-	2091748..2091948 (-)	201	WP_000180460.1	DUF1128 family protein	-
FORC62_RS10955 (FORC62_1969)	-	2092095..2092559 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
FORC62_RS10960 (FORC62_1970)	-	2092566..2092841 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
FORC62_RS10965 (FORC62_1971)	-	2093119..2094336 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
FORC62_RS10970 (FORC62_1972)	vraR	2094449..2095078 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
FORC62_RS10975 (FORC62_1973)	vraS	2095068..2096111 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
FORC62_RS10980 (FORC62_1974)	liaF	2096108..2096809 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
FORC62_RS10985 (FORC62_1975)	-	2096824..2097210 (-)	387	WP_001110179.1	hypothetical protein	-
FORC62_RS10990 (FORC62_1976)	map	2097427..2098185 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
FORC62_RS11000 (FORC62_1977)	-	2098716..2099702 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
FORC62_RS11010 (FORC62_1978)	-	2100133..2100546 (-)	414	WP_001557448.1	hypothetical protein	-
FORC62_RS11015	-	2100575..2100685 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=241003 FORC62_RS10975 WP_001017131.1 2095068..2096111(-) (vraS) [Staphylococcus aureus strain FORC_062]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=241003 FORC62_RS10975 WP_001017131.1 2095068..2096111(-) (vraS) [Staphylococcus aureus strain FORC_062]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1