Detailed information NTG0024073

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: BLI_RS13615
• Genome accession: NC_006322
• Coordinates: 2645724..2648111 (-)
• Length: 795 a.a.
• NCBI ID: WP_009327865.1
• Uniprot ID: Q8VQ75
• Organism: Bacillus licheniformis DSM 13 = ATCC 14580
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2640724..2653111

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BLI_RS13585 (BLi02744)	-	2640993..2641316 (-)	324	WP_003183676.1	YqxA family protein	-
BLI_RS13590 (BLi02745)	spoIIP	2641332..2642537 (-)	1206	WP_003183678.1	stage II sporulation protein P	-
BLI_RS13595 (BLi02746)	gpr	2642656..2643762 (-)	1107	WP_009327867.1	GPR endopeptidase	-
BLI_RS13600 (BLi02747)	rpsT	2643967..2644233 (+)	267	WP_003183682.1	30S ribosomal protein S20	-
BLI_RS13605 (BLi02748)	holA	2644295..2645338 (-)	1044	WP_009327866.1	DNA polymerase III subunit delta	-
BLI_RS21870 (BLi02749)	-	2645568..2645699 (+)	132	WP_003183686.1	YqzM family protein	-
BLI_RS13615 (BLi02750)	comEC	2645724..2648111 (-)	2388	WP_009327865.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
BLI_RS13620 (BLi02751)	-	2648115..2648684 (-)	570	WP_003183690.1	ComE operon protein 2	-
BLI_RS13625 (BLi02752)	comEA	2648753..2649382 (-)	630	WP_003183693.1	helix-hairpin-helix domain-containing protein	Machinery gene
BLI_RS13630 (BLi02753)	comER	2649466..2650287 (+)	822	WP_011198131.1	late competence protein ComER	-
BLI_RS13635 (BLi02754)	-	2650357..2651112 (-)	756	WP_011198132.1	class I SAM-dependent DNA methyltransferase	-
BLI_RS13640 (BLi02755)	rsfS	2651109..2651465 (-)	357	WP_003183699.1	ribosome silencing factor	-
BLI_RS13645 (BLi02756)	yqeK	2651479..2652042 (-)	564	WP_003183701.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
BLI_RS13650 (BLi02757)	-	2652032..2652601 (-)	570	WP_003183702.1	nicotinate-nucleotide adenylyltransferase	-
BLI_RS13655 (BLi02758)	yhbY	2652620..2652910 (-)	291	WP_003183704.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 795 a.a.
• Molecular weight: 87815.76 Da
• Isoelectric Point: 8.3336

>NTDB_id=24073 BLI_RS13615 WP_009327865.1 2645724..2648111(-) (comEC) [Bacillus licheniformis DSM 13 = ATCC 14580]
MDRHRIFPCGAISAAAGIASAHSSLYLFLAVGFFLFFILCFFKKQILLFALCAAVCILYFTSFYVIDHFNTTIYHEGKFH
TLASVQDIPVIDGDRLSFTAETDEGEALKAGYTLRSPQEKRALSALQPGSLCVMQGELKEPKKETVPGTFNQKESMYQKG
IHWIFAVQSITSCKPGGGLMPSLLKIRKAGLDFIEENMADSAAGIGRALIFGDRFLIEQDVLDGYQRLGIIHLLAISGLH
VGLLSAALFYIFIRFGVTRECAKWLLVIGLPVAAVLTGGAPSVMRAVFMSEIYLLASLSKKNFKSADVISIACLGLLLYH
PYLLFQAGFQLSFAVSFVFILSKEILTRPKSRISQLLLGSFLAQLASLPILLFHFQEFSFLSTLMNLFFIPLYIFIIMPL
SFGSLLAFICFHPLGEAAAAVLDRLLVWSHQAVKTVSAADVSVFSAAKPPDLLLFFYFTAIFLFLLLLEKEMSLRAVMIP
SGLLAAVFVIHACLPQLAGEGEVTMLDIGQGDSMYVSAPGQNGTVFIDTGGTVSFRKERWRKRKKDFSLGESVLMPFLAT
KGVKKLDALILTHADQDHIGEAHVLIQKHKVKQLIVPKGFAAEPSDEKLLRLALKEGVEVNVAKRGDILHIGNLEFYVLS
PKEADKNSKNNGSLVLWMKAGGFSWLLTGDLEKEGEKEMMEVYPNLKADILKVGHHGSKGSTGEELIKQIEPKTALISAG
EHNRYGHPHGEVLDILNRHDVKVFRTDRHGSIQHLFRGGNGTFLLHPPYDKVHSPQEKMTAEKQQSSKSRLPDGE

Nucleotide

• Length: 2388 bp

>NTDB_id=24073 BLI_RS13615 WP_009327865.1 2645724..2648111(-) (comEC) [Bacillus licheniformis DSM 13 = ATCC 14580]
ATGGACAGACATCGCATCTTCCCGTGCGGAGCGATTTCAGCGGCAGCCGGAATCGCCTCCGCTCACTCTTCTCTTTATCT
CTTCCTCGCCGTCGGTTTTTTTCTGTTCTTTATCCTCTGTTTCTTCAAAAAACAAATACTCCTTTTCGCTTTATGTGCAG
CGGTTTGTATTTTATATTTTACTTCTTTTTACGTGATCGACCATTTCAATACAACGATTTATCATGAAGGCAAATTTCAC
ACGCTCGCTTCTGTTCAGGATATTCCCGTAATAGACGGAGACCGGCTTTCTTTCACAGCCGAAACAGATGAGGGAGAAGC
TTTGAAAGCGGGATATACGCTCCGGTCTCCACAAGAAAAACGGGCGCTCTCAGCTCTTCAGCCGGGCAGCCTCTGTGTCA
TGCAAGGTGAATTAAAAGAGCCGAAAAAAGAGACGGTTCCTGGCACTTTTAATCAAAAAGAATCCATGTATCAAAAAGGG
ATTCACTGGATTTTTGCAGTTCAGTCTATTACAAGCTGCAAGCCGGGCGGCGGCCTGATGCCATCTCTATTGAAAATCAG
AAAAGCGGGCCTTGATTTTATAGAGGAAAATATGGCGGACTCGGCTGCCGGTATTGGAAGAGCGCTAATTTTCGGAGACC
GGTTTCTCATTGAACAAGATGTCCTGGACGGCTATCAGCGTCTTGGAATCATTCACCTTTTAGCGATTTCCGGGCTTCAT
GTCGGTCTGCTCTCAGCCGCTCTGTTTTACATATTTATTCGCTTCGGCGTCACGAGGGAATGCGCAAAATGGCTGCTCGT
GATCGGCCTTCCCGTTGCCGCAGTTTTGACCGGAGGCGCCCCGTCGGTGATGAGAGCGGTTTTCATGTCTGAAATCTATC
TGCTGGCATCACTGTCTAAAAAGAACTTCAAAAGTGCCGATGTGATCAGCATTGCCTGCCTCGGACTGCTGCTGTATCAT
CCTTATCTGTTATTTCAAGCCGGATTCCAGCTTTCTTTTGCTGTATCCTTCGTTTTCATTCTTTCAAAGGAGATATTGAC
CAGGCCGAAAAGCCGAATCTCTCAGCTGCTATTGGGGTCATTTTTGGCTCAGCTCGCTTCCCTCCCGATTCTGCTTTTTC
ATTTTCAAGAGTTTTCATTTCTCAGCACATTAATGAATCTATTTTTTATACCTCTTTATATTTTCATCATCATGCCGCTG
TCTTTCGGAAGCCTGCTTGCTTTCATATGTTTTCATCCCTTGGGGGAGGCGGCAGCCGCCGTTCTTGACCGTCTGCTTGT
GTGGAGCCATCAGGCTGTTAAAACGGTGTCTGCCGCGGATGTTTCGGTCTTTTCTGCGGCTAAGCCGCCGGATCTTTTGT
TGTTTTTCTACTTCACAGCCATTTTTCTGTTTTTGCTGTTGCTGGAAAAAGAGATGTCGCTTCGTGCGGTCATGATTCCG
TCCGGCCTGCTTGCTGCTGTGTTTGTGATTCACGCATGTCTTCCTCAGCTTGCAGGTGAGGGAGAGGTTACAATGCTTGA
TATCGGCCAAGGGGACAGCATGTATGTCAGCGCTCCCGGTCAGAATGGCACGGTCTTCATTGATACGGGAGGAACCGTAT
CCTTCCGGAAAGAGCGGTGGAGAAAGCGGAAGAAGGATTTTTCATTGGGGGAGAGCGTGTTAATGCCTTTTCTGGCAACC
AAAGGGGTCAAGAAGCTCGATGCTTTAATTTTGACCCATGCTGATCAGGATCATATCGGTGAAGCGCATGTGCTGATCCA
AAAACATAAAGTGAAGCAATTGATCGTGCCGAAAGGCTTCGCAGCCGAACCGTCTGATGAAAAGCTGCTTCGCCTTGCCT
TGAAGGAAGGCGTCGAGGTGAATGTAGCCAAAAGAGGTGACATCCTTCATATTGGCAATCTTGAATTTTATGTTCTTTCA
CCGAAAGAGGCGGACAAAAACAGCAAAAACAATGGTTCCCTCGTATTGTGGATGAAAGCAGGCGGATTTTCGTGGCTGTT
AACTGGAGATTTGGAGAAGGAGGGCGAAAAGGAGATGATGGAAGTGTATCCGAATCTTAAAGCGGATATTCTGAAAGTCG
GTCACCATGGAAGCAAAGGTTCGACGGGTGAAGAGCTGATCAAGCAAATTGAGCCGAAAACCGCCCTCATTTCGGCGGGG
GAGCACAACCGCTACGGGCATCCCCACGGGGAAGTGCTGGACATCCTAAACCGCCACGATGTGAAGGTGTTCAGAACGGA
TCGGCACGGTTCGATTCAGCACCTATTTCGAGGCGGGAACGGAACGTTTTTGCTACATCCTCCATATGATAAAGTACATT
CCCCGCAAGAAAAAATGACTGCTGAAAAACAGCAGTCGTCAAAAAGCCGCTTGCCTGACGGAGAGTAA

Domains

Predicted by InterProScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (509-720)

• Competence protein (Competence) (209-470)

• Domain of unknown function (DUF4131) (DUF4131) (24-171)

3D structure

• AlphaFold DB: Q8VQ75

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	48.235	96.226	0.464