Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   CF389_RS08695 Genome accession   NZ_CP022556
Coordinates   1826170..1826826 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain NJAU-Z9     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1821170..1831826
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CF389_RS08675 spxH 1821409..1822311 (+) 903 WP_003155024.1 protease adaptor protein SpxH -
  CF389_RS19400 - 1822597..1822764 (+) 168 WP_003155026.1 hypothetical protein -
  CF389_RS08685 pepF 1822802..1824631 (-) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  CF389_RS08690 - 1824859..1826019 (-) 1161 WP_003155030.1 competence protein CoiA family protein -
  CF389_RS08695 mecA 1826170..1826826 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  CF389_RS19405 - 1826809..1826919 (-) 111 Protein_1691 adaptor protein MecA -
  CF389_RS08700 - 1827102..1827758 (+) 657 WP_003155033.1 TerC family protein -
  CF389_RS08705 spx 1827816..1828211 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  CF389_RS08710 - 1828390..1828968 (-) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  CF389_RS08715 - 1829086..1830273 (-) 1188 WP_003155036.1 putative glycoside hydrolase -
  CF389_RS08720 oppF 1830380..1831297 (-) 918 WP_003155037.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=240721 CF389_RS08695 WP_003155032.1 1826170..1826826(-) (mecA) [Bacillus velezensis strain NJAU-Z9]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=240721 CF389_RS08695 WP_003155032.1 1826170..1826826(-) (mecA) [Bacillus velezensis strain NJAU-Z9]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGAAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment