Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   C7M29_RS05315 Genome accession   NZ_CP028217
Coordinates   1017873..1019075 (+) Length   400 a.a.
NCBI ID   WP_015250812.1    Uniprot ID   A0ABU0V6N7
Organism   Bacillus subtilis strain SRCM102751     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1012873..1024075
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7M29_RS05295 (C7M29_01044) walK 1012954..1014789 (+) 1836 WP_024572714.1 cell wall metabolism sensor histidine kinase WalK -
  C7M29_RS05300 (C7M29_01045) walH 1014779..1016146 (+) 1368 WP_003226936.1 WalRK two-component regulatory system regulator WalH -
  C7M29_RS05305 (C7M29_01046) walI 1016133..1016975 (+) 843 WP_161476546.1 WalRK two-component regulatory system regulator WalI -
  C7M29_RS05310 (C7M29_01047) vicX 1016997..1017791 (+) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  C7M29_RS05315 (C7M29_01048) htrA 1017873..1019075 (+) 1203 WP_015250812.1 serine protease HtrC Regulator
  C7M29_RS05320 - 1019096..1019222 (+) 127 Protein_981 hypothetical protein -
  C7M29_RS05325 (C7M29_01049) - 1019219..1019719 (-) 501 WP_161476547.1 PepSY domain-containing protein -
  C7M29_RS05330 (C7M29_01050) - 1019880..1020779 (-) 900 WP_015250814.1 PepSY domain-containing protein -
  C7M29_RS05335 (C7M29_01051) - 1020991..1021674 (+) 684 WP_038428106.1 response regulator transcription factor -
  C7M29_RS05340 (C7M29_01052) - 1021671..1023122 (+) 1452 WP_161476548.1 HAMP domain-containing sensor histidine kinase -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42756.50 Da        Isoelectric Point: 5.5340

>NTDB_id=240325 C7M29_RS05315 WP_015250812.1 1017873..1019075(+) (htrA) [Bacillus subtilis strain SRCM102751]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNTVTK
IVSNVSPAVVGVVNIQKSDIRGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=240325 C7M29_RS05315 WP_015250812.1 1017873..1019075(+) (htrA) [Bacillus subtilis strain SRCM102751]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGTAAAAAAGGATATTTTCTTTCTAG
CCTGATTGGTGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTAGATACAGGCG
CCTTAGATCAGCAGCAGAACAATAACGGACGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATACGGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTGGGTGTGGTGAACATCCAAAAATCAGATATACGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGATCGCGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGATCTG
GCCGTTTTACGGGTGAAAAGCGATAAAATTAAAGCAGTCGCTGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCTGGCTCTGTCACACAAGGCGTCATCTCGGGTACGGAGAGGG
CGATCCCAGTAGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGCGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCAGCGGT
TGAAGGGATTGGCCTGTCCATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCGCTAAGCGACATTGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AATGTCACCAATGGAGCGGTTGTGATGGGTGTAGATGCCTTTTCACCTGCCGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTTGACATCAAGCTGTCGTCCGCAGACCAATTAGGAAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Peptidase family M50 (Peptidase_M50)

(196-395)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.791

100

0.42
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.758

82.5

0.378
  htrA Streptococcus pneumoniae D39

45.758

82.5

0.378
  htrA Streptococcus pneumoniae Rx1

45.758

82.5

0.378
  htrA Streptococcus pneumoniae R6

45.758

82.5

0.378

Multiple sequence alignment