Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/comEC   Type   Machinery gene
Locus tag   TTH_RS09990 Genome accession   NC_006461
Coordinates   1842023..1844056 (+) Length   677 a.a.
NCBI ID   WP_011229052.1    Uniprot ID   Q5SGW2
Organism   Thermus thermophilus HB8     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1837023..1849056
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TTH_RS09955 (TTHA1961) - 1837799..1838263 (+) 465 WP_011229049.1 hypothetical protein -
  TTH_RS09960 (TTHA1962) pfkA 1838240..1839208 (-) 969 WP_011173968.1 6-phosphofructokinase -
  TTH_RS09965 (TTHA1963) rsmI 1839205..1839999 (-) 795 WP_011229050.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  TTH_RS09970 (TTHA1964) - 1840001..1840495 (-) 495 WP_011229051.1 hypothetical protein -
  TTH_RS09975 (TTHA1965) - 1840559..1841086 (-) 528 WP_011173971.1 inorganic diphosphatase -
  TTH_RS09980 (TTHA1966) - 1841119..1841745 (+) 627 WP_011173972.1 YcxB family protein -
  TTH_RS09985 (TTHA1967) comEA 1841718..1842026 (+) 309 WP_024119555.1 helix-hairpin-helix domain-containing protein Machinery gene
  TTH_RS09990 (TTHA1968) comA/comEC 1842023..1844056 (+) 2034 WP_011229052.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  TTH_RS09995 (TTHA1969) - 1844044..1844853 (-) 810 WP_011229053.1 ParB/RepB/Spo0J family partition protein -
  TTH_RS10000 (TTHA1970) soj 1844837..1845586 (-) 750 WP_011229054.1 chromosome-partitioning ATPase Soj -
  TTH_RS10005 (TTHA1971) rsmG 1845580..1846329 (-) 750 WP_011229055.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  TTH_RS10010 (TTHA1972) mnmG 1846329..1848122 (-) 1794 WP_011229056.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG -

Sequence

Protein


Download         Length: 677 a.a.        Molecular weight: 71898.98 Da        Isoelectric Point: 10.1641

>NTDB_id=24021 TTH_RS09990 WP_011229052.1 1842023..1844056(+) (comA/comEC) [Thermus thermophilus HB8]
MRPSWTWGVGLGAGALVAAWGLFAPWAFLGLGLLPFLRLPFALGFGLVLARALLFPLPEPPWGAAVEGVFAVRGGFTRAE
GHLLWVSHYPPLPDGRYRLRGRIAPPQGRTNPGGFDQRAWLLSRGAKGVLRAESAEPLGPLPDWREGFRERLGAGLSLEA
REVVEGLVLGDKGGLETAYPLFQRAGLAHLLALSGLHVGVLVGFAVLGLYPLGRWRYLLALALLPFYLLLAGPSPSLVRA
SLMAGLSLLGLFLGLGGAGVVQALGLALFLQLLLRPEALLGLGFQLSYLAVLGLALVLPALRLPPGPRGYLLGGVAASLA
VQAFLLPLLLHRFGFAPLLAPLANLLALPLVALLVPLGFLKLFLGALPAPLVEPLARGLLLLAGLAAQGPLLRWGEIAPP
GFALYYLGLLPLLFALHRRLPWRRALLLASLPTLVGLLAARPKPLDLWMLDVGQGDALLARMGGGEVLVDGGRAEKGEAV
VRALRALGVEALELLVATHPDADHYGGLFRVIEEVPVGLALLAPGFPEDHPLAQALRARGVPVVRAGAGTRLKVGQGEVR
VLWPEALSGDDNQDGLALLLDFGRGRALLLADLPREVEARLPVGEVEALKVSHHGSQSGTSEVLLERTRPRVALIGVGPN
PFGHPHPEVLERLERHGAEVRRTDQDGAVRVLFGYAW

Nucleotide


Download         Length: 2034 bp        

>NTDB_id=24021 TTH_RS09990 WP_011229052.1 1842023..1844056(+) (comA/comEC) [Thermus thermophilus HB8]
ATGAGGCCTTCTTGGACCTGGGGAGTGGGGCTTGGGGCGGGGGCTTTGGTGGCCGCCTGGGGGCTTTTCGCGCCTTGGGC
CTTCCTTGGGCTCGGCCTCCTTCCCTTCCTCCGCCTTCCCTTCGCCCTGGGCTTCGGCCTCGTCCTGGCCCGGGCCCTCC
TCTTCCCCTTGCCCGAGCCCCCGTGGGGCGCCGCCGTGGAGGGGGTCTTCGCCGTGAGGGGCGGGTTCACACGGGCGGAG
GGCCACCTCCTCTGGGTGAGCCACTATCCCCCTCTACCGGACGGCCGCTACCGCCTCCGGGGGCGCATCGCCCCGCCCCA
AGGCCGGACCAACCCCGGGGGGTTTGACCAACGGGCCTGGCTCCTGAGCCGGGGGGCCAAGGGGGTGCTCCGGGCCGAAA
GCGCCGAGCCCTTGGGGCCCCTGCCCGACTGGAGGGAGGGGTTCCGGGAACGCCTAGGGGCGGGCCTGAGCCTCGAGGCC
CGGGAGGTGGTGGAGGGCCTGGTCCTCGGGGACAAGGGGGGCTTAGAGACGGCCTACCCCCTCTTCCAGCGGGCGGGCCT
CGCCCACCTCCTGGCGCTCTCTGGCCTTCACGTGGGGGTGCTCGTGGGCTTCGCCGTCCTCGGCCTCTACCCCCTGGGGC
GGTGGCGCTACCTCCTGGCCCTCGCCCTCCTCCCCTTCTACCTCCTCCTCGCCGGGCCGAGCCCCTCCCTGGTGCGGGCG
AGCCTCATGGCGGGCCTGTCCCTCCTCGGCCTCTTCCTGGGCCTTGGGGGGGCCGGGGTGGTCCAGGCCCTGGGGCTCGC
CCTCTTCCTCCAGCTCCTCCTCCGCCCCGAGGCCCTCCTCGGCCTCGGGTTCCAGCTCTCCTACCTCGCGGTGCTGGGCC
TGGCCCTGGTCCTCCCGGCCCTGAGGCTTCCCCCGGGCCCCAGGGGCTATCTCCTCGGGGGCGTGGCCGCAAGCCTGGCC
GTCCAGGCCTTCCTCCTCCCCCTCCTCCTCCACCGCTTCGGCTTCGCCCCCCTCCTCGCCCCCCTCGCCAACCTCCTCGC
CCTCCCCCTGGTGGCCCTCCTCGTGCCCCTCGGCTTCCTCAAGCTCTTCCTCGGCGCCCTCCCCGCCCCCCTGGTGGAGC
CCCTCGCCCGGGGGCTCCTCCTCCTGGCGGGGCTTGCGGCCCAAGGGCCCCTCCTCCGCTGGGGGGAGATCGCCCCCCCA
GGCTTTGCCCTCTACTACCTGGGCCTTCTCCCCCTCCTTTTCGCCCTCCACCGCAGGCTTCCCTGGCGGCGCGCCCTCCT
CCTCGCCTCCCTGCCCACCCTGGTGGGCCTCCTCGCCGCCCGGCCAAAGCCGCTGGACCTCTGGATGCTGGACGTGGGCC
AGGGGGACGCCCTCCTCGCCCGCATGGGGGGCGGGGAGGTCCTGGTGGACGGGGGACGGGCGGAGAAGGGGGAGGCGGTG
GTCCGGGCCCTCCGCGCCCTCGGGGTGGAGGCCCTGGAGCTTTTGGTGGCCACCCACCCCGACGCGGACCACTACGGGGG
GCTTTTCCGGGTGATAGAGGAGGTTCCCGTGGGCCTTGCCCTCCTCGCCCCCGGCTTCCCCGAGGACCACCCCCTGGCCC
AGGCCCTAAGGGCGCGGGGCGTCCCCGTGGTGCGGGCCGGGGCGGGAACCCGCCTTAAGGTGGGCCAGGGCGAGGTCCGG
GTGCTCTGGCCCGAGGCCCTCTCCGGGGACGACAACCAAGACGGCCTCGCCCTCCTCCTGGACTTCGGCCGGGGACGGGC
CCTCCTCCTCGCCGACCTGCCCCGGGAGGTGGAGGCCAGGCTTCCCGTGGGGGAGGTGGAGGCGCTCAAGGTGAGCCACC
ACGGCTCCCAAAGCGGCACCTCCGAGGTCCTCCTGGAAAGGACGAGGCCCCGGGTGGCCCTCATCGGGGTGGGGCCCAAC
CCCTTCGGCCACCCCCACCCCGAGGTCCTGGAGCGCCTTGAGCGCCACGGCGCGGAGGTGCGCCGCACCGACCAGGACGG
GGCGGTGCGCGTCCTCTTCGGCTACGCCTGGTAG

Domains

Predicted by InterproScan.

Competence protein (Competence)

(167-418)

Domain of unknown function (DUF4131) (DUF4131)

(93-136)

Metallo-beta-lactamase superfamily (Lactamase_B)

(451-635)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5SGW2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/comEC Thermus thermophilus HB27

99.261

100

0.993
  comEC Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

40.85

90.399

0.369

Multiple sequence alignment