Detailed information NTG0024015

Bioinformatically predicted

Overview

• Name: pilQ
• Type: Machinery gene
• Locus tag: TTH_RS07005
• Genome accession: NC_006461
• Coordinates: 1318515..1320788 (+)
• Length: 757 a.a.
• NCBI ID: WP_011228639.1
• Uniprot ID: Q5SII6
• Organism: Thermus thermophilus HB8
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1313515..1325788

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
TTH_RS06975 (TTHA1377)	-	1313637..1314128 (+)	492	WP_011173430.1	DUF5317 domain-containing protein	-
TTH_RS06980 (TTHA1378)	-	1314183..1315187 (+)	1005	WP_011173431.1	homoisocitrate dehydrogenase	-
TTH_RS06985 (TTHA1379)	pilM	1315323..1316456 (+)	1134	WP_011228636.1	type IV pilus assembly protein PilM	Machinery gene
TTH_RS06990 (TTHA1380)	pilN	1316449..1317072 (+)	624	WP_011228637.1	competence protein	Machinery gene
TTH_RS06995 (TTHA1381)	pilO	1317062..1317643 (+)	582	WP_011173434.1	type 4a pilus biogenesis protein PilO	Machinery gene
TTH_RS07000 (TTHA1382)	pilW	1317640..1318518 (+)	879	WP_011228638.1	competence protein	Machinery gene
TTH_RS07005 (TTHA1383)	pilQ	1318515..1320788 (+)	2274	WP_011228639.1	secretin N-terminal domain-containing protein	Machinery gene
TTH_RS07010 (TTHA1384)	aroC	1320847..1321998 (+)	1152	WP_011228640.1	chorismate synthase	-
TTH_RS07015 (TTHA1385)	-	1322023..1322577 (+)	555	WP_008632876.1	shikimate kinase	-
TTH_RS07020 (TTHA1386)	-	1322555..1323601 (+)	1047	WP_011228641.1	3-dehydroquinate synthase family protein	-
TTH_RS07025 (TTHA1387)	rsmF	1323647..1325017 (-)	1371	WP_011228642.1	16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF	-
TTH_RS07030 (TTHA1388)	-	1325070..1325447 (+)	378	WP_011173441.1	4'-phosphopantetheinyl transferase superfamily protein	-
TTH_RS07035 (TTHA1389)	-	1325425..1325778 (-)	354	WP_011228643.1	DUF4870 domain-containing protein	-

Sequence

Protein

• Length: 757 a.a.
• Molecular weight: 82690.81 Da
• Isoelectric Point: 5.2152

>NTDB_id=24015 TTH_RS07005 WP_011228639.1 1318515..1320788(+) (pilQ) [Thermus thermophilus HB8]
MKSAWIRAAVIALAGLGAFALAGSFPEEPRFQAPVNLKVSESQVKAGQTLPLDVVLEALARSVGLQPLIYRAYDPSGDPA
KAQPPLPNIKLDFQGKPFREVWDLLFATYGNQYSLDYLFLPPDVVVVAPTQVITALVDAPSRTGAMERRPYIVGIPEIAY
KRTETDAQGQPRTVVNIEGAKAWVQNDLLPFLSREAAGLNVNWIVVEEGGRLKAVLSVLATPEQHARFSDILQRAGIDFR
PLPALAQPKPRVEKTYTLTYATFPELLAFLQSRLPEAQISVVPTNPQRAIVLATEEDHARLSELLKTADVPKTVRRVYAL
QNLTFAEAQERLKPLLEKDLKGARLESLPGNPKALLLEAPEAEHALFAEILKALDVPPQAPQAPQEATLRRLYPLRYANA
EQVAPFLAREVPGIVVQTVPGQPVLSVRGTEKQLAEVESLLAQIDRAPEQGPPVFQRAYQLSNAKAVELAQVLQEALKAR
QAQNQGQQNQALPTREATVVADPRTNTLIVTGTQEDLALVEGLIPKLDQPVPQVSLRVRIQEVQSNLTRSLGLKWNSIAG
GNVAASILDSGLSLIFDSTRSLAALNIMATLDALQQQGLSRALRDVNQTVLNNQTARLQSGETFFIRRVVNDQVERVPFD
VGLIVEVTPQITADGQILLNIKAEISGNVQRNPVDGDVDRFTKQVVTTTLRVKDGETVVLGGLTSQESNQSQQGVPLLMD
IPLIGELFKQRTNESTDKELLVVITADILKETASANP

Nucleotide

• Length: 2274 bp

>NTDB_id=24015 TTH_RS07005 WP_011228639.1 1318515..1320788(+) (pilQ) [Thermus thermophilus HB8]
ATGAAGAGCGCGTGGATCCGTGCGGCCGTGATCGCCCTCGCAGGGCTAGGGGCTTTTGCCCTTGCGGGGAGCTTTCCCGA
GGAGCCCCGCTTCCAGGCCCCGGTGAACCTCAAGGTCTCGGAATCCCAGGTCAAGGCGGGCCAGACCCTGCCCCTGGACG
TGGTCCTCGAGGCCCTGGCAAGGAGCGTGGGGCTTCAGCCCCTCATCTACCGGGCCTACGACCCAAGCGGGGACCCCGCC
AAGGCCCAGCCCCCCCTGCCCAACATCAAGCTGGACTTCCAGGGCAAGCCCTTCCGGGAGGTCTGGGACCTCCTCTTCGC
CACCTACGGCAACCAGTACAGCCTGGACTACCTCTTCCTGCCCCCCGACGTGGTGGTGGTGGCCCCCACCCAGGTGATCA
CCGCCCTGGTGGACGCCCCGAGCCGCACGGGGGCCATGGAGCGTAGGCCCTACATCGTGGGCATCCCCGAGATCGCCTAC
AAGCGCACGGAGACGGACGCCCAGGGCCAGCCCCGCACGGTCGTCAACATTGAGGGCGCCAAGGCCTGGGTCCAGAACGA
CCTCCTCCCCTTCCTCTCCCGGGAGGCCGCGGGGCTCAACGTGAACTGGATCGTGGTGGAGGAGGGCGGGAGGCTCAAGG
CCGTTCTCTCCGTTCTCGCCACCCCCGAGCAGCACGCCCGCTTCTCCGACATTCTGCAGCGGGCCGGGATTGACTTCCGC
CCCCTCCCCGCCCTGGCCCAGCCCAAGCCCCGGGTGGAGAAGACCTACACCCTCACCTACGCCACCTTCCCCGAACTCCT
CGCCTTCCTCCAGTCCCGCCTCCCCGAGGCCCAGATCAGCGTGGTCCCCACCAACCCCCAAAGGGCCATCGTCCTCGCCA
CCGAGGAGGACCACGCCCGCTTGAGCGAGCTTCTAAAGACGGCCGACGTCCCCAAGACCGTCCGCCGGGTCTACGCCCTG
CAGAACCTCACCTTCGCTGAGGCCCAGGAGCGCCTAAAGCCCCTCCTGGAGAAGGACCTCAAGGGGGCCCGCCTGGAAAG
CCTCCCCGGCAACCCCAAGGCCCTCCTCCTCGAGGCCCCCGAGGCGGAGCACGCCCTCTTCGCCGAGATCCTGAAGGCCC
TGGACGTCCCCCCCCAGGCCCCCCAAGCCCCCCAGGAGGCCACCTTGCGGCGCCTCTACCCCCTGCGCTACGCCAACGCC
GAGCAGGTGGCCCCCTTCCTCGCCCGGGAGGTGCCGGGGATCGTGGTCCAGACCGTTCCCGGCCAGCCCGTCCTCTCGGT
GCGGGGCACGGAGAAGCAGCTCGCCGAGGTGGAAAGCCTCCTCGCCCAGATTGACCGGGCCCCCGAGCAAGGCCCTCCCG
TGTTCCAGCGGGCCTACCAGCTCTCCAACGCCAAGGCGGTGGAGCTCGCCCAGGTGCTCCAGGAGGCGCTCAAGGCCCGG
CAGGCCCAAAACCAGGGCCAGCAGAACCAGGCCCTCCCCACCCGGGAGGCCACGGTGGTGGCCGACCCCAGGACCAACAC
CCTCATCGTCACCGGCACCCAGGAGGACCTCGCCCTGGTGGAGGGCCTCATCCCCAAGCTGGACCAGCCCGTGCCCCAGG
TTTCCTTGCGGGTGCGCATCCAGGAGGTCCAGTCCAACCTGACCCGTAGCCTCGGCCTCAAGTGGAACAGCATCGCCGGC
GGCAACGTGGCGGCCAGCATCCTGGACTCGGGCCTTTCCCTCATCTTTGACTCCACGCGAAGCCTCGCCGCCCTCAACAT
CATGGCCACCCTGGACGCCCTGCAGCAACAGGGCCTCTCCCGGGCCCTCCGGGACGTGAACCAGACCGTCCTCAACAACC
AGACCGCCCGCCTGCAGTCCGGCGAGACCTTCTTCATCCGGCGGGTGGTGAACGACCAGGTGGAACGGGTCCCCTTTGAC
GTGGGGCTCATCGTGGAGGTCACGCCCCAGATCACCGCCGACGGCCAGATCCTCCTCAACATCAAGGCCGAGATCTCGGG
GAACGTCCAGCGCAACCCCGTGGACGGGGACGTGGACCGCTTCACCAAGCAGGTGGTGACCACCACCCTCAGGGTCAAAG
ACGGGGAGACCGTGGTCCTCGGGGGCCTCACCTCCCAGGAGTCCAACCAGAGCCAGCAGGGGGTGCCCCTCCTCATGGAC
ATCCCCCTGATCGGCGAACTCTTCAAGCAGCGGACGAACGAGAGCACCGACAAGGAGCTTTTGGTGGTGATCACCGCCGA
CATCCTCAAGGAGACGGCCTCGGCGAACCCCTAA

Domains

Predicted by InterproScan.

• Bacterial type II/III secretion system short domain (Secretin_N) (457-533)

• Bacterial type II/III secretion system short domain (Secretin_N) (391-450)

• Bacterial type II and III secretion system protein (Secretin) (593-750)

3D structure

• AlphaFold DB: Q5SII6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilQ	Thermus thermophilus HB27	98.018	100	0.98