Detailed information NTG0240115

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: C7M27_RS18585
• Genome accession: NZ_CP028213
• Coordinates: 3580474..3581556 (-)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis strain SRCM102749
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3575474..3586556

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7M27_RS18560 (C7M27_03668)	cysE	3575579..3576232 (-)	654	WP_003225749.1	serine O-acetyltransferase	-
C7M27_RS18565 (C7M27_03669)	gltX	3576534..3577985 (-)	1452	WP_014478617.1	glutamate--tRNA ligase	-
C7M27_RS18570 (C7M27_03670)	ispF	3578076..3578552 (-)	477	WP_003225745.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
C7M27_RS18575 (C7M27_03671)	ispD	3578545..3579243 (-)	699	WP_032726598.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
C7M27_RS18580 (C7M27_03672)	yacL	3579258..3580358 (-)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
C7M27_RS18585 (C7M27_03673)	disA	3580474..3581556 (-)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
C7M27_RS18590 (C7M27_03674)	radA/sms	3581560..3582936 (-)	1377	WP_015252992.1	DNA repair protein RadA	Machinery gene
C7M27_RS18595 (C7M27_03675)	clpC	3583028..3585460 (-)	2433	WP_049140374.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
C7M27_RS18600 (C7M27_03676)	mcsB	3585457..3586548 (-)	1092	WP_003235007.1	protein arginine kinase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=240115 C7M27_RS18585 WP_003225736.1 3580474..3581556(-) (disA) [Bacillus subtilis strain SRCM102749]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=240115 C7M27_RS18585 WP_003225736.1 3580474..3581556(-) (disA) [Bacillus subtilis strain SRCM102749]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGTTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCGGGTCAAAAGATCCTCTACGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCTATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAATATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTTAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTCCTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGACATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCTGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTTCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTACCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1