Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   TTH_RS02270 Genome accession   NC_006461
Coordinates   409940..410854 (-) Length   304 a.a.
NCBI ID   WP_011227933.1    Uniprot ID   -
Organism   Thermus thermophilus HB8     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 404940..415854
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TTH_RS02240 (TTHA0430) hisH 405570..406166 (+) 597 WP_011172519.1 imidazole glycerol phosphate synthase subunit HisH -
  TTH_RS02245 (TTHA0431) - 406137..407057 (-) 921 WP_011227930.1 carbohydrate kinase family protein -
  TTH_RS02250 (TTHA0432) guaB 407202..408683 (+) 1482 WP_011227931.1 IMP dehydrogenase -
  TTH_RS02255 (TTHA0433) - 408680..408910 (-) 231 WP_011172522.1 hypothetical protein -
  TTH_RS02260 (TTHA0434) - 408951..409436 (+) 486 WP_011227932.1 hypothetical protein -
  TTH_RS02265 (TTHA0435) - 409381..409806 (-) 426 WP_011172524.1 disulfide bond formation protein B -
  TTH_RS02270 (TTHA0436) pilA 409940..410854 (-) 915 WP_011227933.1 signal recognition particle-docking protein FtsY Machinery gene
  TTH_RS02275 (TTHA0437) - 410854..411294 (-) 441 WP_011227934.1 hypothetical protein -
  TTH_RS02280 (TTHA0438) gltX 411311..412717 (-) 1407 WP_011227935.1 glutamate--tRNA ligase -
  TTH_RS02285 (TTHA0439) lptB 412772..413500 (+) 729 WP_011172528.1 LPS export ABC transporter ATP-binding protein -
  TTH_RS11440 - 413503..414846 (+) 1344 WP_011227936.1 DUF3084 domain-containing protein -
  TTH_RS11445 prmC 414748..415641 (-) 894 Protein_437 peptide chain release factor N(5)-glutamine methyltransferase -

Sequence

Protein


Download         Length: 304 a.a.        Molecular weight: 32721.17 Da        Isoelectric Point: 9.7124

>NTDB_id=24003 TTH_RS02270 WP_011227933.1 409940..410854(-) (pilA) [Thermus thermophilus HB8]
MGLFDRLRAGLAKTRERLLKAIPWGGDPEEVLEELEMALLAADVGVAATEELLKEVRASGRRDLKEVVKEKLVQMLEPDE
RRATLRKLGFRPQKLRPVEPQGHVVMVVGVNGVGKTTTIAKLGRLYQGLGKKVLFCAGDTFRAAGGAQLAEWGKRLGIPV
IQGPEGADPAALAFDAAKARRARGLDLLFVDTAGRLHTKQGLMEELKKVKRAIAKADPGEPGEVWLVLDAVTGQNGLEQA
KRFHEAVGLTGVIVTKLDGTAKGGVLVPIVRTLKVPIRFIGVGEGPDDLQPFDAEAFVEALLEA

Nucleotide


Download         Length: 915 bp        

>NTDB_id=24003 TTH_RS02270 WP_011227933.1 409940..410854(-) (pilA) [Thermus thermophilus HB8]
ATGGGCCTCTTTGACCGGCTCAGGGCGGGCCTCGCCAAGACCCGGGAAAGGCTCCTCAAGGCCATCCCCTGGGGCGGCGA
CCCCGAGGAGGTCCTGGAGGAGCTGGAGATGGCCCTCCTCGCCGCCGACGTGGGGGTGGCGGCCACGGAGGAGCTCCTCA
AGGAGGTGCGGGCCTCGGGGCGGCGGGACCTGAAGGAGGTGGTGAAGGAGAAGCTCGTCCAGATGCTGGAGCCGGACGAG
CGGCGGGCCACGCTGAGGAAGCTCGGCTTCCGTCCCCAGAAGCTCCGCCCCGTGGAGCCTCAGGGGCACGTGGTGATGGT
GGTGGGGGTGAACGGGGTGGGCAAGACCACCACCATCGCCAAGCTGGGCCGCCTCTACCAGGGCCTCGGCAAGAAGGTCC
TCTTCTGCGCCGGGGACACCTTCCGCGCCGCGGGGGGAGCCCAGCTTGCGGAGTGGGGGAAGCGCCTCGGGATCCCGGTG
ATCCAGGGCCCGGAAGGGGCGGACCCCGCCGCCCTCGCCTTTGACGCCGCCAAGGCCCGAAGGGCGCGGGGCCTGGACCT
CCTCTTCGTGGACACCGCGGGCCGCCTCCACACCAAGCAGGGCCTCATGGAGGAGCTCAAGAAGGTGAAGCGGGCCATCG
CCAAGGCGGACCCCGGGGAGCCGGGGGAGGTGTGGCTCGTGCTGGACGCCGTCACCGGGCAAAACGGCCTGGAGCAGGCC
AAGCGCTTTCACGAGGCCGTGGGCCTCACCGGGGTCATCGTCACCAAGCTGGACGGGACGGCCAAGGGCGGGGTCCTGGT
CCCCATCGTCCGCACCCTAAAGGTGCCCATCCGCTTCATCGGCGTGGGAGAAGGCCCGGACGACCTCCAGCCCTTTGACG
CCGAGGCCTTCGTGGAGGCCCTCCTCGAGGCCTGA

Domains

Predicted by InterproScan.

SRP54-type protein, helical bundle domain (SRP54_N)

(29-65)

SRP54-type protein, GTPase domain (SRP54)

(103-302)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

48.726

100

0.503

Multiple sequence alignment