Detailed information NTG0239637

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: C7M17_RS15145
• Genome accession: NZ_CP028202
• Coordinates: 2890695..2891777 (-)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis strain SRCM102754
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2885695..2896777

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7M17_RS15120 (C7M17_02987)	cysE	2885800..2886453 (-)	654	WP_003225749.1	serine O-acetyltransferase	-
C7M17_RS15125 (C7M17_02988)	gltX	2886755..2888206 (-)	1452	WP_014478617.1	glutamate--tRNA ligase	-
C7M17_RS15130 (C7M17_02989)	ispF	2888297..2888773 (-)	477	WP_046159975.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
C7M17_RS15135 (C7M17_02990)	ispD	2888766..2889464 (-)	699	WP_017695824.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
C7M17_RS15140 (C7M17_02991)	yacL	2889479..2890579 (-)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
C7M17_RS15145 (C7M17_02992)	disA	2890695..2891777 (-)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
C7M17_RS15150 (C7M17_02993)	radA/sms	2891781..2893157 (-)	1377	WP_015252992.1	DNA repair protein RadA	Machinery gene
C7M17_RS15155 (C7M17_02994)	clpC	2893249..2895681 (-)	2433	WP_014475592.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
C7M17_RS15160 (C7M17_02995)	mcsB	2895678..2896769 (-)	1092	WP_003235007.1	protein arginine kinase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=239637 C7M17_RS15145 WP_003225736.1 2890695..2891777(-) (disA) [Bacillus subtilis strain SRCM102754]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=239637 C7M17_RS15145 WP_003225736.1 2890695..2891777(-) (disA) [Bacillus subtilis strain SRCM102754]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGCTGGCTAAAATGGATGGTGCGATC
ATTTTAAGTGATTCGGGTCAAAAGATCCTCTATGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCTATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAATATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTTAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGAACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCCGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTTCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTACCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1